Thioketone-Directed Palladium(II)-Catalyzed C-H Arylation of Ferrocenes with Aryl Boronic Acids

被引：55

作者：

Cai, Zhong-Jian ^{[1
]}

Liu, Chen-Xu ^{[1
]}

Gu, Qing ^{[1
]}

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 05期

基金：

中国博士后科学基金; 国家重点研发计划;

关键词：

arylation; C-H activation; ferrocenes; palladium; sulfur; PLANAR CHIRAL FERROCENES; CATALYZED DIRECT ARYLATION; DEHYDROGENATIVE ANNULATION; BOND FUNCTIONALIZATION; BENZYL THIOETHERS; ACTIVATION; CARBON; ALKYLATION; SP(2); ALKENYLATION;

D O I：

10.1002/anie.201711451

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium(II)-catalyzed thioketone-chelation-assisted direct C-H arylation of ferrocenes is described. With thioketone as an efficient directing group, various monoaryl- and diaryl-substituted thiocarbonylferrocenes were obtained by palladium-catalyzed direct C-H functionalization in high yields under mild and base-free reaction conditions. Furthermore, the arylated thiocarbonylferrocene could undergo diverse transformations.

引用

页码：1296 / 1299

页数：4

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