A case report of clozapine augmentation with granulocyte colony stimulating factor (G-CSF)

被引：3

作者：

Broughton, Trevor ^{[1
]}

Millward, Tim ^{[1
]}

Geelan, Steve ^{[1
]}

机构：

[1] E England Forens Mental Hlth Serv, Leicester LE5 0LE, Leics, England

来源：

JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY | 2012年 / 23卷 / 01期

关键词：

clozapine; neutropenia; granulocyte colony stimulating factor; INDUCED NEUTROPENIA; RECHALLENGE; LITHIUM; TERM;

D O I：

10.1080/14789949.2011.633096

中图分类号：

DF [法律]; D9 [法律];

学科分类号：

0301 ;

摘要：

For some patients clozapine represents the only option for controlling the debilitating symptoms of schizophrenia. More tragic are those cases where previously successful treatment with clozapine is withdrawn as a result of blood dyscrasia. In this article, the authors describe such a case. In this instance it was possible to continue treatment with clozapine to good effect by using granulocyte colony stimulating factor (G-CSF) as an adjunct. This article further explores the decision-making process and the clinical evidence behind this approach.

引用

页码：125 / 133

页数：9