Phenolic glycosides from the filamentous fungus Acremonium sp BCC 14080

被引：16
作者：
Bunyapaiboonsri, Taridaporn [1 ]
Yoiprommarat, Seangaroon [1 ]
Khonsanit, Artit [1 ]
Komwijit, Somjit [1 ]
机构：
[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Klongluang 12120, Pathumthani, Thailand
来源：
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 05期
关键词：
D O I：
10.1021/np070689m
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
New phenolic mono- and digalactopyranosides (1 and 2), their aglycone KS-501a (3), and a new phenolic 4-O-methylglucopyranoside (4) were isolated from the filamentous fungus Acremonium sp. BCC 14080. Structures of these compounds were elucidated by extensive MS and NMR spectroscopic analyses. Compound 1 displayed anti-HSV-1 activity with an IC(50) value of 7.2 mu M. Compound 3 exhibited activity against Plasmodium falciparum K1 with an IC(50) value of 9.9 mu M.
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页码：891 / 894
页数：4
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