Concise Total Synthesis of Permethylated Anigopreissin A, a New Benzofuryl Resveratrol Dimer

被引：32
作者：
Chiummiento, Lucia [1 ]
Funicello, Maria [1 ]
Lopardo, Maria Teresa [1 ]
Lupattelli, Paolo [1 ]
Choppin, Sabine [2 ]
Colobert, Francoise [2 ]
机构：
[1] Univ Basilicata, Dipartimento Chim Antonio Mario Tamburro, I-85100 Potenza, Italy
[2] Univ Strasbourg, CNRS, UMR 7509, Lab Stereochim,ECPM, F-67087 Strasbourg 2, France
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 01期
关键词：
Natural products; Total synthesis; Cross-coupling; Palladium; Heterocycles; SONOGASHIRA REACTIONS; PALLADIUM CATALYSTS; FRAGMENT;
D O I：
10.1002/ejoc.201101422
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The versatile preparation of permethylated anigopreissin A (1) has been accomplished from methyl 3,5-dihydroxybenzoate. The key steps of the synthesis are sequential Sonogashira and Suzuki cross-couplings for the construction of the 2,3-diarylbenzo[b]furan moiety and Wittig olefination for the introduction of the styryl group.
引用
收藏
页码：188 / 192
页数：5
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