The new Clostridium difficile -: What does it mean?

被引:102
作者
Bartlett, JG [1 ]
Perl, TM [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA
关键词
D O I
10.1056/NEJMe058221
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
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页码:2503 / 2505
页数:3
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共 12 条
[1]   ANTIBIOTIC-ASSOCIATED PSEUDOMEMBRANOUS COLITIS DUE TO TOXIN-PRODUCING CLOSTRIDIA [J].
BARTLETT, JG ;
CHANG, TW ;
GURWITH, M ;
GORBACH, SL ;
ONDERDONK, AB .
NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (10) :531-534
[2]   CYTO-TOXICITY ASSAY IN ANTIBIOTIC-ASSOCIATED COLITIS [J].
CHANG, TW ;
LAUERMANN, M ;
BARTLETT, JG .
JOURNAL OF INFECTIOUS DISEASES, 1979, 140 (05) :765-770
[3]   A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality [J].
Loo, VG ;
Poirier, L ;
Miller, MA ;
Oughton, M ;
Libman, MD ;
Michaud, S ;
Bourgault, AM ;
Nguyen, T ;
Frenette, C ;
Kelly, M ;
Vibien, A ;
Brassard, P ;
Fenn, S ;
Dewar, K ;
Hudson, TJ ;
Horn, R ;
René, P ;
Monczak, Y ;
Dascal, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (23) :2442-2449
[4]   An epidemic, toxin gene-variant strain of Clostridium difficile [J].
McDonald, LC ;
Killgore, GE ;
Thompson, A ;
Owens, RC ;
Kazakova, SV ;
Sambol, SP ;
Johnson, S ;
Gerding, DN .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (23) :2433-2441
[5]   NOSOCOMIAL ACQUISITION OF CLOSTRIDIUM-DIFFICILE INFECTION [J].
MCFARLAND, LV ;
MULLIGAN, ME ;
KWOK, RYY ;
STAMM, WE .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (04) :204-210
[6]   A large outbreak of Clostridium Difficile -: Associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use [J].
Muto, CA ;
Pokrywka, M ;
Shutt, K ;
Mendelsohn, AB ;
Nouri, K ;
Posey, K ;
Roberts, T ;
Croyle, K ;
Krystofiak, S ;
Patel-Brown, S ;
Pasculle, AW ;
Paterson, DL ;
Saul, M .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2005, 26 (03) :273-280
[7]   Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003:: a changing pattern of disease severity [J].
Pépin, J ;
Valiquette, L ;
Alary, ME ;
Villemure, P ;
Pelletier, A ;
Forget, K ;
Pépin, K ;
Chouinard, D .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 171 (05) :466-472
[8]   Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea:: A cohort study during an epidemic in Quebec [J].
Pépin, J ;
Saheb, N ;
Coulombe, MA ;
Alary, ME ;
Corriveau, MP ;
Authier, S ;
Leblanc, M ;
Rivard, G ;
Bettez, M ;
Primeau, V ;
Nguyen, M ;
Jacob, CE ;
Lanthier, L .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (09) :1254-1260
[9]   Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates [J].
Spigaglia, P ;
Mastrantonio, P .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (09) :3470-3475
[10]   CLINDAMYCIN-ASSOCIATED COLITIS - PROSPECTIVE STUDY [J].
TEDESCO, FJ ;
BARTON, RW ;
ALPERS, DH .
ANNALS OF INTERNAL MEDICINE, 1974, 81 (04) :429-433