Optimising low molecular weight hydrogels for automated 3D printing

被引：72

作者：

Nolan, Michael C. ^{[1
,2
]}

Fuentes Caparros, Ana M. ^{[1
,3
]}

Dietrich, Bart ^{[1
]}

Barrow, Michael ^{[2
]}

Cross, Emily R. ^{[1
]}

Bleuel, Markus ^{[4
,5
]}

King, Stephen M. ^{[6
]}

Adams, Dave J. ^{[1
]}

机构：

[1] Univ Glasgow, Sch Chem, Glasgow G12 8QQ, Lanark, Scotland

[2] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

[3] Fac Sci, Dept Chem Engn, Granada 18071, Spain

[4] NIST, NIST Ctr Neutron Res, Gaithersburg, MD 20988 USA

[5] Univ Maryland, Dept Mat Sci & Engn, College Pk, MD 20742 USA

[6] Rutherford Appleton Lab, Sci & Technol Facil Council, STFC Pulsed Neutron & Muon Source, Harwell Campus, Didcot OX11 0QX, Oxon, England

来源：

SOFT MATTER | 2017年 / 13卷 / 45期

基金：

英国工程与自然科学研究理事会; 美国国家科学基金会;

关键词：

MECHANICAL-PROPERTIES; DRUG-DELIVERY; DESIGN;

D O I：

10.1039/c7sm01694h

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points. These interactions can allow hydrogels to recover quickly after a high shear rate has been applied. There are currently limited design rules describing which types of morphology or rheological properties are required for a LMWG hydrogel to be used as an effective, printable gel. By preparing hydrogels with different types of fibrous network structures, we have been able to understand in more detail the morphological type which gives rise to a 3D-printable hydrogel using a range of techniques, including rheology, small angle scattering and microscopy.

引用

页码：8426 / 8432

页数：7

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