Synthesis of Quinoxaline Analogues

被引：11
|
作者：
Chang, Meng-Yang [1 ]
Lee, Tein-Wei [1 ]
Hsu, Ru-Ting [2 ]
Yen, Tzu-Lin [3 ]
机构：
[1] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 807, Taiwan
[2] ShuZen Coll Med & Management, Dept Nursing, Kaohsiung 821, Taiwan
[3] Kaohsiung Med Univ, Dept Nursing, Kaohsiung Municipal Hsiao Kang Hosp, Kaohsiung 807, Taiwan
来源：
SYNTHESIS-STUTTGART | 2011年 / 19期
关键词：
condensation; halogenation; tandem reactions; heterocycles; arenes; ALPHA-HYDROXY KETONES; SOLID-PHASE SYNTHESIS; EFFICIENT SYNTHESIS; CATALYZED SYNTHESIS; MOLECULAR-IODINE; TANDEM OXIDATION; AMMONIUM-NITRATE; DERIVATIVES; DIHYDROPYRAZINES; CYCLIZATION;
D O I：
10.1055/s-0030-1260147
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Substituted tricyclic or tetracyclic quinoxalines, tricyclic pyridoquinoxalines and bis-quinoxalines were synthesized in high yields starting from cyclic ketones by the alpha-bromination of cyclic ketones with N-bromosuccinimide (NBS) followed by condensation of the resulting alpha-bromo ketones with 1,2-diaminobenzene, 3,4-diaminopyridine, or 3,3'-diaminobenzidine.
引用
收藏
页码：3143 / 3151
页数：9
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