Total ocular akinesis: Miller Fisher or Guillain-Barre syndrome?

被引：0

作者：

Rajska, Kinga ^{[1
]}

Rozniecki, Jacek ^{[2
]}

Loba, Piotr ^{[3
]}

Zielinska, Malgorzata ^{[2
]}

Broniarczyk-Loba, Anna ^{[1
]}

机构：

[1] Uniwersytet Med Lodzi, Zaklad Patofizjol Widzenia Obuocznego & Leczenia, Katedry Chorob Oczu, PL-90153 Lodz, Poland

[2] Uniwersytet Med Lodzi, Neurol Klin, PL-90153 Lodz, Poland

[3] Uniwersytet Med Lodzi, Klin Chorob Oczu, Katedry Chorob Oczu, PL-90153 Lodz, Poland

来源：

NEUROLOGIA I NEUROCHIRURGIA POLSKA | 2011年 / 45卷 / 03期

关键词：

ophthalmoplegia; Miller Fisher syndrome; Guillain-Barre syndrome; IGG ANTIBODY;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Total, bilateral ophthalmoplegia is very rare. More than 50% of cases are Miller Fisher (MFS) and Guillain-Barre (GBS) syndromes. There is a correlation of MFS with anti-GQ1b antibodies. High levels of GQ1b gangliosides are found in myelin sheathes of cranial nerves supplying the extraocular muscles. This may explain the association of anti-GQ1b antibodies with ophthalmoplegia. Anti-GQ1b were also found in cases of GBS accompanied by ophthalmoplegia, atypical MFS (IMF'S without ataxia), MFS/GBS overlap syndromes and Bickerstaff brainstem encephalitis. This has led some authors to classify them as 'anti-GQ1b syndromes'. In this article we describe a diagnostically difficult case of a patient with a very rare, total bilateral paralysis of all ocular muscles, accompanied by bilateral ptosis, diminished tendon reflexes of upper extremities, paresis and hypoesthesia of the left upper extremity.

引用

页码：297 / 300

页数：4

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