Effects of Plant Extracts on Dentin Bonding Strength: A Systematic Review and Meta-Analysis

被引:6
作者
Zhao, Shikai [1 ,2 ]
Hua, Fang [3 ,4 ]
Yan, Jiarong [1 ,2 ]
Yang, Hongye [1 ,2 ,5 ]
Huang, Cui [1 ,2 ,5 ]
机构
[1] Wuhan Univ, State Key Lab Breeding Base Basic Sci Stomatol Hu, Sch & Hosp Stomatol, Wuhan, Hubei, Peoples R China
[2] Wuhan Univ, Key Lab Oral Biomed, Sch & Hosp Stomatol, Minist Educ, Wuhan, Hubei, Peoples R China
[3] Wuhan Univ, Sch & Hosp Stomatol, Dept Orthodont, Ctr Evidence Based Stomatol, Wuhan, Peoples R China
[4] Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth, Div Dent,Sch Med Sci, Manchester, Lancs, England
[5] Wuhan Univ, Sch & Hosp Stomatol, Dept Prosthodont, Wuhan, Peoples R China
基金
中国国家自然科学基金;
关键词
dentin; bonding; plant extracts; natural crosslinkers; adhesives; primers; ETCH-AND-RINSE; ADHESIVE INTERFACE; EPIGALLOCATECHIN-3-GALLATE EGCG; METALLOPROTEINASE INHIBITORS; ANTIBACTERIAL ACTIVITIES; RESIN; POLYPHENOLS; DEGRADATION; DURABILITY; FLAVONOIDS;
D O I
10.3389/fbioe.2022.836042
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Objective: To systematically review in vitro studies that evaluated the effects of plant extracts on dentin bonding strength.Materials and Methods: Six electronic databases (PubMed, Embase, VIP, CNKI, Wanfang and The Cochrane Library) were searched from inception to September 2021 in accordance with the Preferred Reporting Items for Systematic Reviews (PRISMA). In vitro studies that compared the performance of dental adhesives with and without the plant extracts participation were included. The reference lists of the included studies were manually searched. Two researchers carried out study screening, data extraction and risk of bias assessment, independently and in duplicate. Meta-analysis was conducted using Review Manager 5.3.Results: A total of 62 studies were selected for full-text analysis. 25 articles used the plant extracts as primers, while five added the plant extracts into adhesives. The meta-analysis included 14 articles of in vitro studies investigating the effects of different plant extract primers on dentin bonding strength of etch-and-rinse and self-etch adhesives, respectively. The global analysis showed statistically significant difference between dental adhesives with and without plant extract primers. It showed that the immediate bond strength of dental adhesives was improved with the application of plant extract primers.Conclusion: The application of proanthocyanidin (PA) primers have positive effect on the in vitro immediate bonding strength of dental adhesives irrespective of etch-and-rinse or self-etch modes.
引用
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页数:13
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