Palladium-Mediated Olefination of 2-(tert-Butyldimethylsilyl)pyridine by sp3 C-H Activation

被引：5
|
作者：
Wang, Cong [1 ]
Ge, Haibo [1 ]
机构：
[1] Indiana Univ Purdue Univ, Dept Chem & Chem Biol, Indianapolis, IN 46202 USA
来源：
SYNTHESIS-STUTTGART | 2011年 / 16期
基金：
美国国家科学基金会;
关键词：
palladium; olefination; pyridine; CROSS-COUPLING REACTIONS; BOND FUNCTIONALIZATION; DIRECT ARYLATION; CARBON; ARENES; ALKENYLATION; ACYLATION; CATALYSTS; ACIDS;
D O I：
10.1055/s-0030-1260075
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unprecedented direct alkenylation of 2-(tert-butyldimethylsilyl)pyridine with acrylates through palladium-mediated C-H activation on a nonacidic sp(3) carbon is reported. This method provides an efficient approach to allylsilanes.
引用
收藏
页码：2590 / 2594
页数：5
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