An efficient chemoselective synthesis of pyrido[2,3-d]pyrimidine derivatives under microwave irradiation

被引：31
|
作者：
Tu, Shujiang [1 ]
Li, Chunmei [1 ]
Shi, Feng [1 ]
Zhou, Dianxiang [1 ]
Shao, Qingqing [1 ]
Cao, Longji [1 ]
Jiang, Bo [1 ]
机构：
[1] Xuzhou Normal Univ, Sch Chem & Chem Engn, Key Lab Biotechnol Med Plant, Xuzhou 221116, Jiangsu, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2008年 / 03期
关键词：
solvent-dependent chemoselectivity; pyrido[2,3-d]pyrimidines; microwave irradiation; heterocycles; multicomponent reaction;
D O I：
10.1055/s-2008-1032031
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and selective synthesis of poly-substituted pyrido [2,3-d]pyrimidines is accomplished via microwave-assisted multicomponent reactions controlled by the nature of solvent. In addition, a possible mechanism accounting for the reaction is proposed.
引用
收藏
页码：369 / 376
页数：8
相关论文
共 50 条
  • [1] An Efficient Microwave-assisted Synthesis of Pyrido[2,3-d]pyrimidine Derivatives
    Tu Shujiang
    Wu Shanshan
    Han Zhengguo
    Hao Wenjuan
    CHINESE JOURNAL OF CHEMISTRY, 2009, 27 (06) : 1148 - 1152
  • [2] Efficient Synthesis of Pyridine [2,3-d]pyrimidine Derivatives by Catalyst-free Tandem Cyclization Under Microwave Irradiation
    Lin, Junjie
    Wang, Shuang
    Li, Weiqiang
    Cui, Xin
    Huang, Chao
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2020, 41 (12): : 2749 - 2758
  • [3] Microwave-assisted multicomponent reaction: An efficient synthesis of indolyl substituted and spiroxindole pyrido[2,3-d]pyrimidine derivatives
    Wang, Jing
    Zhu, Shuang
    Liu, Yanni
    Zhu, Xiaotong
    Shi, Kexin
    Li, Xiang
    Zhu, Songlei
    SYNTHETIC COMMUNICATIONS, 2022, 52 (01) : 85 - 95
  • [4] Ecofriendly synthesis of substituted pyridine and pyrido[2,3-d]pyrimidine derivatives
    Kidwai, M
    Thakur, R
    Rastogi, S
    RUSSIAN CHEMICAL BULLETIN, 2005, 54 (06) : 1523 - 1526
  • [5] Ecofriendly synthesis of substituted pyridine and pyrido[2,3-d]pyrimidine derivatives
    M. Kidwai
    R. Thakur
    S. Rastogi
    Russian Chemical Bulletin, 2005, 54 : 1523 - 1526
  • [6] New potential inhibitors of cyclin-dependent kinase-4:: Design and synthesis of pyrido[2,3-d]pyrimidine derivatives under microwave irradiation
    Tu, Shujiang
    Zhang, Jinpeng
    Zhu, Xiaotong
    Xu, Jianing
    Zhang, Yan
    Wang, Qian
    Jia, Runhong
    Jiang, Bo
    Zhang, Junyong
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (13) : 3578 - 3581
  • [7] Efficient synthesis ofpyrano[2,3-d]pyrimidinone and pyrido[2,3-d]pyrimidine derivatives in presence of novel basic ionic liquid catalyst
    Jolodar, Omid Goli
    Shirini, Farhad
    Seddighi, Mohadeseh
    CHINESE JOURNAL OF CATALYSIS, 2017, 38 (07) : 1245 - 1251
  • [8] A Facile and Efficient Synthesis of Spiro[indoline-3,5'-pyrido[2,3-d]pyrimidine] Derivatives via Microwave-assisted Multicomponent Reactions
    Wang, Jing
    Li, Jie
    Liu, Hongzhi
    Xu, Zhou
    Zhu, Songlei
    LETTERS IN ORGANIC CHEMISTRY, 2015, 12 (01) : 62 - 66
  • [9] Efficient one-pot synthesis of pyrano[2,3-d]pyrimidinone and pyrido [2,3-d] pyrimidine derivatives by using of Mn-ZIF-8@ZnTiO3 nanocatalyst
    Farahmand, Tayebeh
    Hashemian, Saeedeh
    Sheibani, Ali
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1206
  • [10] Sodium Formate-Catalyzed One-Pot Synthesis of Functionalized Spiro[indoline-3,5′-pyrido[2,3-d]pyrimidine]/Spiro[acenaphthylene-1,5′-pyrido[2,3-d]-pyrimidine] Derivatives
    Nurjamal, Khondekar
    Brahmachari, Goutam
    CHEMISTRYSELECT, 2019, 4 (08): : 2363 - 2367
12345