Clostridium difficile infection An overview of the disease and its pathogenesis, epidemiology and interventions

被引：89

作者：

Viswanathan, V. K. ^{[1
]}

Mallozzi, M. J. ^{[1
]}

Vedantam, Gayatri ^{[1
,2
]}

机构：

[1] Univ Arizona, Dept Vet Sci & Microbiol, Tucson, AZ 85721 USA

[2] Southern Arizona VA Healthcare Syst, Res Serv, Tucson, AZ 85723 USA

来源：

GUT MICROBES | 2010年 / 1卷 / 04期

关键词：

Clostridium difficile; infection; CDI; CDAD; hypervirulent; spore; infection control; pathogenesis;

D O I：

10.4161/gmic.1.4.12706

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Clostridium difficile infection (CDI) is the primary cause of antibiotic-associated diarrhea and is a significant nosocomial disease. In the past ten years, variant toxin-producing strains of C. difficile have emerged, that have been associated with severe disease as well as outbreaks worldwide. This review summarizes current information on C. difficile pathogenesis and disease, and highlights interventions used to combat single and recurrent episodes of CDI.

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收藏

页码：234 / 242

页数：9

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