Clostridium difficile infection An overview of the disease and its pathogenesis, epidemiology and interventions

被引：89

作者：

Viswanathan, V. K. ^{[1
]}

Mallozzi, M. J. ^{[1
]}

Vedantam, Gayatri ^{[1
,2
]}

机构：

[1] Univ Arizona, Dept Vet Sci & Microbiol, Tucson, AZ 85721 USA

[2] Southern Arizona VA Healthcare Syst, Res Serv, Tucson, AZ 85723 USA

来源：

GUT MICROBES | 2010年 / 1卷 / 04期

关键词：

Clostridium difficile; infection; CDI; CDAD; hypervirulent; spore; infection control; pathogenesis;

D O I：

10.4161/gmic.1.4.12706

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Clostridium difficile infection (CDI) is the primary cause of antibiotic-associated diarrhea and is a significant nosocomial disease. In the past ten years, variant toxin-producing strains of C. difficile have emerged, that have been associated with severe disease as well as outbreaks worldwide. This review summarizes current information on C. difficile pathogenesis and disease, and highlights interventions used to combat single and recurrent episodes of CDI.

引用

收藏

页码：234 / 242

页数：9

相关论文

共 50 条

[31] Evolving Insights Into the Epidemiology and Control of Clostridium difficile in Hospitals [J].

Caroff, Daniel A. ;

Yokoe, Deborah S. ;

Klompas, Michael .

CLINICAL INFECTIOUS DISEASES, 2017, 65 (07) :1232-1238

[32] Clostridium difficile and inflammatory bowel disease: Role in pathogenesis and implications in treatment [J].

Orna Nitzan ;

Mazen Elias ;

Bibiana Chazan ;

Raul Raz ;

Walid Saliba .

World Journal of Gastroenterology, 2013, 19 (43) :7577-7585

[33] Clostridium difficile disease: Diagnosis, pathogenesis, and treatment update [J].

Napolitano, Lena M. ;

Edmiston, Charles E., Jr. .

SURGERY, 2017, 162 (02) :325-348

[34] Environmental Interventions to Control Clostridium difficile [J].

Loo, Vivian G. .

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2015, 29 (01) :83-+

[35] Clostridium difficile: Changing Epidemiology, Treatment and Infection Prevention Measures [J].

Jane A. Cecil .

Current Infectious Disease Reports, 2012, 14 :612-619

[36] Molecular epidemiology of Clostridium difficile infection in a Brazilian cancer hospital [J].

Costa, Cecilia Leite ;

Mano de Carvalho, Cibele Barreto ;

Gonzalez, Rafael Holanda ;

Cavalcante Gifoni, Markus Andret ;

Ribeiro, Ronaldo de Albuquerque ;

Quesada-Gomez, Carlos ;

de Castro Brito, Gerly Anne .

ANAEROBE, 2017, 48 :232-236

[37] Clostridium difficile Infection: Epidemiology, Clinical Presentation, Therapy and Prevention [J].

Kaffarnik, Magnus ;

Isner, Caroline ;

Hamsen, Uwe .

ZENTRALBLATT FUR CHIRURGIE, 2018, 143 (03) :241-249

[38] Clostridium difficile infection: Is there a change in the underlying factors? Inflammatory bowel disease and Clostridium difficile [J].

Bolukcu, Sibel ;

Hakyemez, Ismail Necati ;

Gultepe, Bilge Sumbul ;

Okay, Gulay ;

Durdu, Bulent ;

Koc, Meliha Meric ;

Aslan, Turan .

SAUDI JOURNAL OF GASTROENTEROLOGY, 2019, 25 (06) :384-389

[39] Chronic kidney disease as a risk factor for Clostridium difficile infection [J].

Eddi, Rodney ;

Malik, Mohammed N. ;

Shakov, Rada ;

Baddoura, Walid J. ;

Chandran, Chandra ;

Debari, Vincent A. .

NEPHROLOGY, 2010, 15 (04) :471-475

[40] Clostridium difficile infection in a patient with Crohn disease [J].

Hsu, Chien-Hui ;

Jeng, Yung-Ming ;

Ni, Yen-Hsuan .

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2012, 111 (06) :347-349

← 1 2 3 4 5 →