1-(Pyrimidin-4-yl)pyrazol-5(4H)-one derivatives: I. Synthesis of 3-methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-pyrazol-5-ol and specificity of its Knoevenagel reaction

被引：4
作者：
Erkin, A. V. [1 ]
Krutikov, V. I. [1 ]
机构：
[1] St Petersburg State Inst Technol, St Petersburg 190013, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2011年 / 81卷 / 02期
关键词：
Pyrazole; Aromatic Aldehyde; Ethyl Acetoacetate; Hydrazono; Knoevenagel Reaction;
D O I：
10.1134/S1070363211020186
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3-Methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-1H-pyrazol-5-ol available via cyclocondensation of 6-methyl-2-methylsulfanylpyrimidin-4-ylhydrazine with ethyl acetoacetate reacted with aromatic aldehydes to give two kinds of products, 4-arylmethylidene-5-oxo-4,5-dihydropyrazole and arylbis(5-hydroxypyrazol-4-yl)methane derivatives, depending on the substituent in the aromatic aldehyde.
引用
收藏
页码：392 / 396
页数：5
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