1-(Pyrimidin-4-yl)pyrazol-5(4H)-one derivatives: I. Synthesis of 3-methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-pyrazol-5-ol and specificity of its Knoevenagel reaction

被引：4

作者：

Erkin, A. V. ^{[1
]}

Krutikov, V. I. ^{[1
]}

机构：

[1] St Petersburg State Inst Technol, St Petersburg 190013, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2011年 / 81卷 / 02期

关键词：

Pyrazole; Aromatic Aldehyde; Ethyl Acetoacetate; Hydrazono; Knoevenagel Reaction;

D O I：

10.1134/S1070363211020186

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-1H-pyrazol-5-ol available via cyclocondensation of 6-methyl-2-methylsulfanylpyrimidin-4-ylhydrazine with ethyl acetoacetate reacted with aromatic aldehydes to give two kinds of products, 4-arylmethylidene-5-oxo-4,5-dihydropyrazole and arylbis(5-hydroxypyrazol-4-yl)methane derivatives, depending on the substituent in the aromatic aldehyde.

引用

页码：392 / 396

页数：5

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