Clinical symptoms of hypogonadism after radical prostatectomy

This study checked whether the prevalence of hypogonadal symptoms [measured using the Aging Males' Symptoms Scale (AMSS)] after radical prostatectomy can give information about: the prevalence of hypogonadism in this group of patients. Distribution of the level of complaints (no, mild, moderate or severe) on the AMSS after radical prostatectomy (n=576) was analyzed in all patient I (G) and stratified by the point in time of data collection [surgery to AMSS less (K1) and more than 1 year (K2)] The total score shows more patient I with mild and moderate symptoms in G, K1, and K2 compared with the control (G 57.6 and 23.4%, K1 59.1 and 22.4%, K2 40 and 35.6% vs 36.5 and 11.2%). In the somatic score G and K1 show 2.4% (G) and 1.7% (K1) less patients with no and 1.5% (G) and 0.9% (K1) less patients with little complaints compared with the control; 2.6% (G) and 1.8% (K1) more patients state moderate and 1.2% (G) and 0.8% (K1) more severe complaints. K2 shows fewer patients with no and mild (22.2 and 31.1% vs 33.3 and 39.3%) and more with moderate and severe complaints (33.3 and 13.3% vs 21.0 and 6.4%) compared with the control. In the psychological score patients in G and K1 state less mild complaints (G 33.9%, K1 32.8% vs 41.8%), more patients state no complaints (G 45.8%, K1 47.3% vs 43.6%) as well as moderate and severe complaints (G 12.8%, K1 12.8% vs 10.9% and G 7.5%, K1 7.2% vs 3.7%) compared with the control. K2 shows more complaints of all levels compared with the control (mild 46.7 vs 41.8%, moderate 13.3 vs 10.9%, and severe 11.1 vs 3.7%). In the sexual score all groups of patients show significantly more severe complaints (G 89.6%, K1 89.5%, K2 91.1% vs 6.1%). Multiple factors influenced by surgery and diagnosis of cancer which are independent of hormonal effects make distribution of hypogonadal symptoms on the AMSS not suitable to give information about the prevalence of hypogonadism after radical prostatectomy. An analysis of serum testosterone seems to be essential.