The "Risk'' in Pediatric Low-Grade Glioma

被引:5
|
作者
Fangusaro, Jason [1 ,2 ,3 ]
Bandopadhayay, Pratiti [4 ,5 ,6 ]
机构
[1] Childrens Healthcare Atlanta, Dept Pediat Hematol & Oncol, Atlanta, GA 30329 USA
[2] Aflac Canc & Blood Disorder Ctr, Atlanta, GA 30322 USA
[3] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA 30322 USA
[4] Dana Farber Boston Childrens Canc & Blood Disorde, Boston, MA USA
[5] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
[6] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
关键词
RECURRENT; CHILDREN;
D O I
10.1016/j.ccell.2020.03.020
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In this issue of Cancer Cell, Ryall et al. report on the largest clinically and molecularly characterized cohort of pediatric low-grade gliomas (pLGGs) published to date. They provide new insight into the pLGG molecular landscape and a novel risk stratification system with the potential to revolutionize prognostication and impact treatment.
引用
收藏
页码:424 / 425
页数:2
相关论文
共 50 条
  • [21] Pseudoprogression in Pediatric Low-Grade Glioma After Radiation Therapy
    Tsang, D. S.
    Murphy, E. S.
    Lucas, J. T., Jr.
    Lagiou, P.
    Acharya, S.
    Merchant, T. E.
    PEDIATRIC BLOOD & CANCER, 2017, 64 : S6 - S6
  • [22] Response of Pediatric Low-grade Glioma to Conformal Radiation Therapy
    Naik, M.
    Berle, L. P.
    Merchant, T. E.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (03): : S506 - S507
  • [23] CLINICAL AND MOLECULAR FEATURES OF DISSEMINATED PEDIATRIC LOW-GRADE GLIOMA
    Levine, Adrian
    Li, Cyril
    Haizel-Cobbina, Joseline
    Nobre, Liana
    Bennett, Julie
    Dewan, Michael
    Tabori, Uri
    Hawkins, Cynthia
    NEURO-ONCOLOGY, 2023, 25
  • [24] Molecular markers and targeted therapy in pediatric low-grade glioma
    de Blank, Peter
    Fouladi, Maryam
    Huse, Jason T.
    JOURNAL OF NEURO-ONCOLOGY, 2020, 150 (01) : 5 - 15
  • [25] Craniospinal irradiation for treatment of metastatic pediatric low-grade glioma
    Tsang, Derek S.
    Murphy, Erin S.
    Ezell, Sharon E.
    Lucas, John T., Jr.
    Tinkle, Christopher
    Merchant, Thomas E.
    JOURNAL OF NEURO-ONCOLOGY, 2017, 134 (02) : 317 - 324
  • [26] Risk Factors for Malignant Transformation of Low-Grade Glioma
    Murphy, Erin S.
    Leyrer, Charles M.
    Parsons, Michael
    Suh, John H.
    Chao, Samuel T.
    Yu, Jennifer S.
    Kotecha, Rupesh
    Jia, Xuefei
    Peereboom, David M.
    Prayson, Richard A.
    Stevens, Glen H. J.
    Barnett, Gene H.
    Vogelbaum, Michael A.
    Ahluwalia, Manmeet S.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 100 (04): : 965 - 971
  • [27] IDENTIFYING NEW VULNERABILITIES TO TARGET PEDIATRIC LOW-GRADE GLIOMA
    Borgenvik, Anna
    Misek, Sean
    Maile, Jens
    Novikov, Dana
    Bahadur, Sher
    Apfelbaum, April
    Morin, Eric
    Condurat, Alexandra
    Gonzales, Elizabeth
    Zhou, Kevin
    Goodale, Amy
    Abid, Tanaz
    Kalani, Zohra
    Piccioni, Federica
    Ligon, Keith
    Beroukhim, Rameen
    Persky, Nicole
    Jones, David
    Root, David
    Bandopadhayay, Pratiti
    NEURO-ONCOLOGY, 2023, 25
  • [28] Molecular markers and targeted therapy in pediatric low-grade glioma
    Peter de Blank
    Maryam Fouladi
    Jason T. Huse
    Journal of Neuro-Oncology, 2020, 150 : 5 - 15
  • [29] Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma
    Neevika Manoharan
    Jungwhan Choi
    Christine Chordas
    Mary Ann Zimmerman
    Jacqueline Scully
    Jessica Clymer
    Mariella Filbin
    Nicole J. Ullrich
    Pratiti Bandopadhayay
    Susan N. Chi
    Kee Kiat Yeo
    Journal of Neuro-Oncology, 2020, 149 : 253 - 262
  • [30] Craniospinal irradiation for treatment of metastatic pediatric low-grade glioma
    Derek S. Tsang
    Erin S. Murphy
    Sharon E. Ezell
    John T. Lucas
    Christopher Tinkle
    Thomas E. Merchant
    Journal of Neuro-Oncology, 2017, 134 : 317 - 324