Target-selective degradation of oligosaccharuides by a light-activated small-molecule lectin hybrid

被引:24
作者
Ishii, Maiko [1 ]
Matsumura, Shuichi [1 ]
Toshima, Kazunobu [1 ]
机构
[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
关键词
anthraquinone; cyclodextrins; lectin; oligosaccharides; photochemistry;
D O I
10.1002/anie.200702127
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) An innovative method for target-selective degradation of oligosaccharides induced by a light-activated hybrid molecule consisting of anthraquinone and lectin has been developed (see scheme). The reaction takes place under neutral conditions, and no additives are required. PNA = peanut agglutinin. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:8396 / 8399
页数:4
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