Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare

被引：20

作者：

Amarsy, Rishma ^{[1
]}

Jacquier, Herve ^{[2
]}

Munier, Anne-Lise ^{[3
]}

Merimeche, Manel ^{[4
]}

Bercot, Beatrice ^{[2
]}

Megarbane, Bruno ^{[5
]}

机构：

[1] Univ Paris, Lariboisiere Hosp, Infect Prevent & Control Team, Paris, France

[2] Univ Paris, Lariboisiere & St Louis Hosp, Lab Bacteriol, Paris, France

[3] Univ Paris, Lariboisiere & St Louis Hosp, Dept Infect Dis, Paris, France

[4] AP HP, MOABI, Bioinformat Platform, Paris, France

[5] Univ Paris, Lariboisiere Hosp, Dept Med & Toxicol Crit Care, Paris, France

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 2021年 / 49卷 / 10期

关键词：

Carbapenemase; COVID-19; Hospital infection control; Transmission; ICU; Enterobacterales;

D O I：

10.1016/j.ajic.2021.07.004

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

An outbreak of Klebsiella pneumoniae producing the carbapenemase NDM-1 occurred in our ICU during the last COVID-19 wave. Twelve patients were tested positive, seven remained asymptomatic whereas 5 developed an infection. Resistome and in silico multilocus sequence typing confirmed the clonal origin of the strains. The identification of a possible environmental reservoir suggested that difficulties in observing optimal bio-cleaning procedures due to workload and exhaustion contributed to the outbreak besides the inappropriate excessive glove use. (c) 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

引用

页码：1324 / 1326

页数：3

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