Electrochemical Enabled Cascade Phosphorylation of N-H/O-H/S-H Bonds with P-H Compounds: An Efficient Access to P(O)-X Bonds

被引：24

作者：

Wang, Ruige ^{[1
,2
]}

Dong, Xiaojuan ^{[1
,2
]}

Zhang, Yonghong ^{[1
,2
]}

Wang, Bin ^{[1
,2
]}

Xia, Yu ^{[1
,2
]}

Abdukader, Ablimit ^{[1
,2
]}

Xue, Fei ^{[1
,2
]}

Jin, Weiwei ^{[1
,2
]}

Liu, Chenjiang ^{[1
,2
]}

机构：

[1] Xinjiang Univ, Coll Chem, Urumqi Key Lab Green Catalysis & Synth Technol, Key Lab Oil & Gas Fine Chem,Minist Educ, Urumqi 830046, Peoples R China

[2] Xinjiang Univ, Coll Chem, Xinjiang Uygur Autonomous Reg State Key Lab Chem, Urumqi 830046, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2021年 / 27卷 / 60期

基金：

中国国家自然科学基金;

关键词：

cross-coupling; electrochemistry; phosphorylation; hydrogen evolution; P(O)-X bonds; METAL; OXIDATION; FUNCTIONALIZATION; SULFIDES; ALCOHOLS; OXIDANT; QUINOXALIN-2(1H)-ONES; PHOSPHONATION; CONSTRUCTION; DERIVATIVES;

D O I：

10.1002/chem.202102262

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An electrochemical three component cascade phosphorylation reaction of various heteroatoms-containing nucleophiles including carbazoles, indoles, phenols, alcohols, and thiols with Ph2PH has been established. Electricity is used as the "traceless" oxidant and water and air are utilized as the "green" oxygen source. All kinds of structurally diverse organophosphorus compounds with P(O)-N/P(O)-O/P(O)-S bonds are assembled in moderate to excellent yields (three categories of phosphorylation products, 50 examples, up to 97 % yield). A tentative free radical course is put forward to rationalize the reaction procedure.

引用

页码：14931 / 14935

页数：5

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