EUROCarbDB: An open-access platform for glycoinformatics

被引：83

作者：

von der Lieth, Claus-Wilhelm ^{[2
]}

Freire, Ana Arda ^{[3
]}

Blank, Dennis ^{[4
]}

Campbell, Matthew P. ^{[5
,6
]}

Ceroni, Alessio ^{[1
]}

Damerell, David R. ^{[1
]}

Dell, Anne ^{[1
]}

Dwek, Raymond A. ^{[6
]}

Ernst, Beat ^{[7
]}

Fogh, Rasmus ^{[8
]}

Frank, Martin ^{[2
]}

Geyer, Hildegard ^{[4
]}

Geyer, Rudolf ^{[4
]}

Harrison, Mathew J. ^{[8
]}

Henrick, Kim ^{[8
]}

Herget, Stefan ^{[2
]}

Hull, William E. ^{[2
]}

Ionides, John ^{[8
]}

Joshi, Hiren J. ^{[2
,8
]}

Kamerling, Johannis P. ^{[3
]}

Leeflang, Bas R. ^{[3
]}

Lutteke, Thomas ^{[3
]}

Lundborg, Magnus ^{[9
]}

Maass, Kai ^{[4
]}

Merry, Anthony ^{[8
]}

Ranzinger, Rene ^{[2
]}

Rosen, Jimmy ^{[3
]}

Royle, Louise ^{[5
,6
]}

Rudd, Pauline M. ^{[5
,6
]}

Schloissnig, Siegfried ^{[2
]}

Stenutz, Roland ^{[9
]}

Vranken, Wim F. ^{[8
]}

Widmalm, Goran ^{[9
]}

Haslam, Stuart M. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Div Mol Biosci, Fac Nat Sci, London SW7 2AZ, England

[2] German Canc Res Ctr, Core Facil, D-6900 Heidelberg, Germany

[3] Univ Utrecht, Bijvoet Ctr Biomol Res, Utrecht, Netherlands

[4] Univ Giessen, Fac Med, Inst Biochem, Giessen, Germany

[5] Univ Coll Dublin, Conway Inst, Dublin Oxford Glycobiol Lab, NIBRT, Dublin 2, Ireland

[6] Univ Oxford, Oxford Glycobiol Inst, Dept Biochem, Oxford OX1 2JD, England

[7] Univ Basel, Dept Pharmaceut Sci, Basel, Switzerland

[8] European Bioinformat Inst, Hinxton, England

[9] Stockholm Univ, S-10691 Stockholm, Sweden

来源：

GLYCOBIOLOGY | 2011年 / 21卷 / 04期

基金：

英国生物技术与生命科学研究理事会;

关键词：

databases; glycoinformatics; informatics tools; open-source; DESORPTION/IONIZATION MASS-SPECTROMETRY; GLYCOPROTEIN GLYCAN STRUCTURES; CURATED RELATIONAL DATABASE; PROTEIN DATA-BANK; NMR-SPECTROSCOPY; N-GLYCANS; GLYCOSYLATION; GLYCOMICS; GLYCOBIOLOGY; TECHNOLOGY;

D O I：

10.1093/glycob/cwq188

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.

引用

页码：493 / 502

页数：10

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