Antibodies in the Treatment of Psoriasis: IL-12/23 p40 and IL-17a

被引：10
|
作者：
Leonardi, Craig L. [1 ]
机构：
[1] St Louis Univ, Cent Dermatol, Dermatol, St Louis, MO 63103 USA
来源：
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY | 2016年 / 35卷
关键词：
IL-12/23; inhibitors; IL-17/IL-17A inhibitors; IL-23; PLACEBO-CONTROLLED TRIAL; TO-SEVERE PSORIASIS; INTERLEUKIN-12/23; MONOCLONAL-ANTIBODY; IL; 12/23; AGENTS; DOUBLE-BLIND; CARDIOVASCULAR EVENTS; PLAQUE PSORIASIS; METAANALYSES; USTEKINUMAB; SAFETY;
D O I：
10.12788/j.sder.2016.021
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
The anti-tumor necrosis factor (TNF)-alpha agents represent the second generation of psoriasis therapy. Research has produced a third generation of biologic treatments, some of which offer greater efficacy than the TNF-alpha inhibitors. This article reviews the data documenting the efficacy and safety of three types of biologics. (C) 2016 published by Frontline Medical Communications
引用
收藏
页码：S74 / S77
页数：4
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