Primary combined squamous and small cell carcinoma of the larynx: a case report and review of the literature

被引：0
作者：
Zhang, Guosheng [1 ]
Chen, Yuanhua [2 ]
Li, Chengwen [4 ]
Liu, Min [3 ]
Qin, Liangqing [1 ]
机构：
[1] Linqu Peoples Hosp, Dept Otolaryngol, Weifang, Shandong, Peoples R China
[2] Linqu Peoples Hosp, Dept Neurol, Weifang, Shandong, Peoples R China
[3] Linqu Peoples Hosp, Dept Pathol, Weifang, Shandong, Peoples R China
[4] Changle Peoples Hosp, Dept Otolaryngol, Changle, Shandong, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2018年 / 11卷 / 09期
关键词：
Combined small cell carcinoma; larynx; treatment; prognosis; NEUROENDOCRINE CARCINOMA;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Primary combined squamous and small cell carcinoma is a rare type of laryngeal carcinoma, and only 18 cases have been reported in the literature. Here we report a 70-year-old male patient presenting with transglottic carcinoma, which was composed of both small cell carcinoma and squamous cell. The patient underwent total laryngectomy with bilateral modified neck dissection and consolidation radiotherapy. We found metastasis in right adrenal gland 16 months after initial diagnosis and the patient died of multi-organ metastase in abdomen. Therefore, this type of laryngeal carcinoma might be a great aggressive tumor. More rational treatment regimen and molecule-targeted drugs to such carcinoma should be developed in the future.
引用
收藏
页码：10136 / 10139
页数：4
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