Mesoporous silicate MCM-41 containing organic ultraviolet ray absorbents: Preparation, photostability and in vitro release

被引：13
作者：
Ambrogi, V.
Perioli, L.
Marmottini, F.
Latterini, L.
Rossi, C.
Costantino, U.
机构：
[1] Dipartimento Chim & Tecnol Farm, I-06123 Perugia, Italy
[2] CEMIN, Dipartimento Chim, I-06123 Perugia, Italy
[3] Dipartimento Ingn Civile & Ambientale, I-06125 Perugia, Italy
来源：
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS | 2007年 / 68卷 / 5-6期
关键词：
organic compounds; inorganic compounds; x-ray diffraction; infrared spectroscopy; differential scanning calorimetry;
D O I：
10.1016/j.jpcs.2007.02.033
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The mesoporous silicate MCM-41 was studied for its properties to adsorb and to influence the photostability and the release of three organic ultraviolet (UV) ray absorbents, namely benzophenone-3 (B3), benzophenone-2 (B2) and p-aminobenzoic acid (PABA). MCM-41 microcrystals have been loaded with the UV absorbents obtaining a good loading w/w percentage. The loaded samples have been characterized by chemical and thermal analyses, X-ray diffraction, N-2 adsorption isotherms. Photochemical studies demonstrated that the UV-shielding properties of B2 were maintained whereas in other cases a small reduction of sunscreen protection range was noticed. B3 and B2 release from loaded MCM-41 formulations were studied and compared to those obtained from formulations containing free UV ray absorbent; no remarkable differences were observed in the release profiles. (c) 2007 Elsevier Ltd. All rights reserved.
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页码：1173 / 1177
页数：5
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