Dietary exposure of the Qatari population to food mycotoxins and reflections on the regulation limits

被引:19
|
作者
Al Jabir, Muna [1 ]
Barcaru, Andrei [2 ,3 ]
Latiff, Aishah [4 ]
Jaganjac, Morana [4 ]
Ramadan, Gouda [1 ]
Horvatovich, Peter [3 ]
机构
[1] Minist Publ Hlth, Publ Hlth Dept, Cent Food Labs, Doha, Qatar
[2] Fac Med Sci, Lab Med, Hanzepl 1, NL-9713 GZ Groningen, Netherlands
[3] Univ Groningen, Groningen Res Inst Pharm, Dept Analyt Biochem, Antonius Deusinglaan 1, NL-9713 AV Groningen, Netherlands
[4] Anti Doping Lab Qatar, Sport City Rd,POB 27775, Doha, Qatar
关键词
Mycotoxin; Risk assessment; Aflatoxin; Ochratoxin; Fumonisin; Margin of exposure; Tolerable daily intake; RISK-ASSESSMENT; AFLATOXIN CONTAMINATION; PESTICIDE-RESIDUES; OCHRATOXIN; PRODUCTS; CONSUMERS;
D O I
10.1016/j.toxrep.2019.09.009
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
The article estimates the exposure of the population of Qatar to aflatoxins, fumonisins and ochratoxins, measured in food samples collected from the markets of Doha. The mycotoxin extractions were performed using the "Quick Easy Cheap Effective Rugged Safe" Method (QuEChERS) and the extract measured with LC-MS/MS. High contamination with aflatoxins was detected in Nuts and Spices (e.g. 534.15 ng/g and 371.6 ng/g respectively). The estimated daily intake (EDI) level was estimated using statistical data on average Qatari population. Additionally, the probability to exceed TDI was calculated for fumonisins and ochratoxins. The results indicate high exposure to aflatoxins (with alarming values of margin of exposure, i.e. MoE). The article points to the necessity of a regular assessment and reevaluation of the concentration limits allowed in food products accounting for statistics on the population (i.e. food consumption), economic growth of the country, and monitoring of mycotoxin contamination of food as much as technological, financial and human resources of a country allows.
引用
收藏
页码:975 / 982
页数:8
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