TREK for High-Speed and High-Frequency Conduction through the Axon

被引：5

作者：

Prado, Pablo Avalos ^{[1
,2
]}

Sandoz, Guillaume ^{[1
,2
]}

机构：

[1] Univ Cote Azur, CNRS, INSERM, iBV, Nice, France

[2] Labs Excellence Ion Channel Sci & Therapeut, Nice, France

来源：

NEURON | 2019年 / 104卷 / 05期

关键词：

D O I：

10.1016/j.neuron.2019.11.015

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this issue of Neuron, Kanda et al. (2019) find that the two-pore domain potassium channels TRAAK and TREK1 drive axonal action potential repolarization for high-speed and high-frequency nervous impulses in mammalian myelinated nerves.

引用

页码：831 / 833

页数：4

共 10 条

[1] The action potential in mammalian central neurons [J].

Bean, Bruce P. .

NATURE REVIEWS NEUROSCIENCE, 2007, 8 (06) :451-465

[2] Sodium channel Nav1.6 is localized at nodes of Ranvier, dendrites, and synapses [J].

Caldwell, JH ;

Schaller, KL ;

Lasher, RS ;

Peles, E ;

Levinson, SR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (10) :5616-5620

[3] POTASSIUM CHANNELS IN NODAL AND INTERNODAL AXONAL MEMBRANE OF MAMMALIAN MYELINATED FIBERS [J].

CHIU, SY ;

RITCHIE, JM .

NATURE, 1980, 284 (5752) :170-171

[4] Aβ-fiber nociceptive primary afferent neurons:: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals [J].

Djouhri, L ;

Lawson, SN .

BRAIN RESEARCH REVIEWS, 2004, 46 (02) :131-145

[5] Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype [J].

Heurteaux, Catherine ;

Lucas, Guillaume ;

Guy, Nicolas ;

El Yacoubi, Malika ;

Thummler, Susanne ;

Peng, Xiao-Dong ;

Noble, Florence ;

Blondeau, Nicolas ;

Widmann, Catherine ;

Borsotto, Marc ;

Gobbi, Gabriella ;

Vaugeois, Jean-Marie ;

Debonnel, Guy ;

Lazdunski, Michel .

NATURE NEUROSCIENCE, 2006, 9 (09) :1134-1141

[6] EVIDENCE FOR ELECTRICAL TRANSMISSION IN NERVE. PART I [J].

Hodgkin, A. L. .

JOURNAL OF PHYSIOLOGY-LONDON, 1937, 90 (02) :183-210

[7] TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves [J].

Kanda, Hirosato ;

Ling, Jennifer ;

Tonomura, Sotatsu ;

Noguchi, Koichi ;

Matalon, Sadis ;

Gu, Jianguo G. .

NEURON, 2019, 104 (05) :960-+

[8] Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels [J].

Levitz, Joshua ;

Royal, Perrine ;

Comoglio, Yannick ;

Wdziekonski, Brigitte ;

Schaub, Sebastien ;

Clemens, Daniel M. ;

Isacoff, Ehud Y. ;

Sandoz, Guillaume .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (15) :4194-4199

[9] Molecular regulations governing TREK and TRAAK channel functions [J].

Noel, Jacques ;

Sandoz, Guillaume ;

Lesage, Florian .

CHANNELS, 2011, 5 (05) :400-407

[10] Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK [J].

Royal, Perrine ;

Andres-Bilbe, Alba ;

Prado, Pablo Avalos ;

Verkest, Clement ;

Wdziekonski, Brigitte ;

Schaub, Sebastien ;

Baron, Anne ;

Lesage, Florian ;

Gasull, Xavier ;

Levitz, Joshua ;

Sandoz, Guillaume .

NEURON, 2019, 101 (02) :232-+

← 1 →