Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

被引：1

作者：

Palanisamy, Senthilkumar ^{[1
]}

Subramanian, Kalaivani ^{[3
]}

Bennet, Lerince Godrina ^{[3
]}

Ambrose, Janani ^{[3
]}

Gopalakrishnan, Aganiya ^{[3
]}

Babu, Sudhagar ^{[4
]}

Rajamani, Ranjithkumar ^{[5
]}

Jha, Niraj Kumar ^{[6
]}

Pandit, Soumya ^{[2
]}

Singh, Sachin Kumar ^{[7
]}

Dua, Kamal ^{[8
,9
]}

Gupta, Piyush Kumar ^{[2
]}

机构：

[1] Nehru Arts & Sci Coll, Dept Biotechnol, Coimbatore 641105, Tamil Nadu, India

[2] Sharda Univ, Sch Basic Sci & Res SBSR, Dept Life Sci, Knowledge Pk 3, Greater Noida 201310, Uttar Pradesh, India

[3] Kongunadu Arts & Sci Coll, Dept Biotechnol, Coimbatore 641029, Tamil Nadu, India

[4] Natl Inst Mental Hlth & Neurosci NIMHANS, Dept Biophys, Struct Biol Lab, Bangalore 560030, Karnataka, India

[5] Viyen Biotech LLP, Coimbatore 641031, Tamil Nadu, India

[6] Sharda Univ, Sch Engn & Technol SET, Dept Biotechnol, Knowledge Pk 3, Greater Noida 201310, Uttar Pradesh, India

[7] Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara 144411, Punjab, India

[8] Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, Sydney, NSW 2007, Australia

[9] Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia

来源：

NANOFABRICATION | 2021年 / 6卷 / 01期

关键词：

pregnant cow urine; chitosan; Ag/AgCl nanoparticles; antimicrobial activity; respiratory tract infection pathogens; EXTRACT-MEDIATED SYNTHESIS; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; GREEN SYNTHESIS; CHITOSAN; CYTOTOXICITY; RESPONSES; BIOFILMS;

D O I：

10.1515/nanofab-2020-0106

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

引用

页码：68 / 78

页数：11

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