Repeatability of autorefraction and axial length measurements after laser in situ keratomileusis

Purpose: To assess the repeatability and agreement of refractive error measurements and the repeatability of axial length (AL) measurements in patients after laser in situ keratomileusis (LASIK). Setting: The Ohio State University College of Optometry, Columbus, Ohio, USA. Methods: Subjective refraction, autorefraction measurements with the Grand Seiko and Humphrey autorefractors, and AL measurements with the IOLMaster were completed for 40 previously myopic LASIK patients under noncycloplegic and cycloplegic conditions on 2 separate occasions. Results: The mean difference between visits for axial length measurements was 0.008 mm +/- 0.04 (SD). The between visits repeatability for all refractive error measurements were < 0.75 diopter (D). The mean difference between the subjective refraction and the Humphrey autorefractor for spherical equivalent was statistically significant under noncycloplegic conditions (-0.90 D, P <.0001) and cycloplegic conditions (-2.05 D, P <.0001). The mean difference between subjective refraction and Grand Seiko autorefraction measurements was not significant under noncycloplegic conditions (+ 0.05 D, 95% limits of agreement [LoA] = -0.99, 1.09; P = .52) conditions but was statistically significant, but not clinically relevant, under cycloplegic conditions (+ 0.17 D, 95% LoA = -0.73, 1.07; P = .03). Conclusions: Refractive error measurements after LASIK using the Grand Seiko autorefractor are reliable and agree well with subjective refraction measurements. (c) 2005 ASCRS and ESCRS.