Pathophysiology, Prevention and Management of Chronic Kidney Disease in the Hypertensive Patient With Diabetes Mellitus

被引：17
作者：
Solini, Anna [1 ]
Ferrannini, Ele [1 ]
机构：
[1] Univ Pisa, Dept Internal Med, I-56100 Pisa, Italy
来源：
JOURNAL OF CLINICAL HYPERTENSION | 2011年 / 13卷 / 04期
关键词：
GLOMERULAR-FILTRATION-RATE; BLOOD-PRESSURE CONTROL; CONVERTING ENZYME-INHIBITORS; CARDIOVASCULAR OUTCOMES; FOLLOW-UP; ANGIOTENSIN-II; NEPHROPATHY; ALBUMINURIA; MORTALITY; SMOKING;
D O I：
10.1111/j.1751-7176.2011.00446.x
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
The authors concisely review the main clinical issues arising in the management of the hypertensive patient with type 2 diabetes, in whom chronic kidney disease is prevalent and heralds increased cardiovascular morbidity and mortality. Special attention is paid to the clinical meaning, relevance and limits of albumin excretion and glomerular filtration rate, the two widely used markers of reduced kidney function during the course of chronic diseases like diabetes and hypertension. The main therapeutic strategies involving blood pressure and glycemic control, treatment of dyslipidemia and improvement of lifestyle are discussed from the viewpoint of a general practitioner dealing with the clinical complexity of these patients. J Clin Hypertens (Greenwich). 2011;13:252-257. (C) 2011 Wiley Periodicals, Inc.
引用
收藏
页码：252 / 257
页数：6
相关论文
共 49 条
[1]   Management of Diabetes in Patients with Chronic Kidney Disease [J].
Ahmed, Ziauddin ;
Simon, Barbara ;
Choudhury, Devasmita .
POSTGRADUATE MEDICINE, 2009, 121 (03) :52-60
[2]  
American Society of Nephrology, 2005, J Am Soc Nephrol, V16, P1886
[3]   Predictors of cardiovascular events in patients with type 2 diabetic nephropathy and hypertension: A case for albuminuria [J].
Anavekar, NS ;
Gans, DJ ;
Berl, T ;
Rohde, RD ;
Cooper, W ;
Bhaumik, A ;
Hunsicker, LG ;
Rouleau, JL ;
Lewis, JB ;
Rosendorff, C ;
Porush, JG ;
Drury, PL ;
Esmatjes, E ;
Raz, I ;
Vanhille, P ;
Locatelli, F ;
Goldhaber, S ;
Lewis, EJ ;
Pfeffer, MA .
KIDNEY INTERNATIONAL, 2004, 66 :S50-S55
[4]   Calcium channel blockade to prevent stroke in hypertension - A meta-analysis of 13 studies with 103,793 subjects [J].
Angeli, F ;
Verdecchia, P ;
Reboldi, GP ;
Gattobigio, R ;
Bentivoglio, M ;
Staessen, AA ;
Porcellati, C .
AMERICAN JOURNAL OF HYPERTENSION, 2004, 17 (09) :817-822
[5]  
[Anonymous], 2007, National Diabetes Fact Sheet
[6]   The changing patterns of chronic kidney disease: The need to develop strategies for prevention relevant to different regions and countries [J].
Atkins, RC .
KIDNEY INTERNATIONAL, 2005, 68 :S83-S85
[7]   Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy [J].
Brenner, BM ;
Cooper, ME ;
de Zeeuw, D ;
Keane, WF ;
Mitch, WE ;
Parving, HH ;
Remuzzi, G ;
Snapinn, SM ;
Zhang, ZX ;
Shahinfar, S .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (12) :861-869
[8]   Estimated glomerular filtration rate, albuminuria and mortality in type 2 diabetes: the Casale Monferrato study [J].
Bruno, G. ;
Merletti, F. ;
Bargero, G. ;
Novelli, G. ;
Melis, D. ;
Soddu, A. ;
Perotto, M. ;
Pagano, G. ;
Cavallo-Perin, P. .
DIABETOLOGIA, 2007, 50 (05) :941-948
[9]   Low glomerular filtration rate in normoalbuminuric type 1 dihibetic patients - An indicator of more advanced glomerular lesions [J].
Caramori, ML ;
Fioretto, P ;
Mauer, M .
DIABETES, 2003, 52 (04) :1036-1040
[10]   Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus [J].
Chakkera, H. A. ;
Bodner, J. K. ;
Heilman, R. L. ;
Mulligan, D. C. ;
Moss, A. A. ;
Mekeel, K. L. ;
Mazur, M. J. ;
Hamawi, K. ;
Ray, R. M. ;
Beck, G. L. ;
Reddy, K. S. .
TRANSPLANTATION PROCEEDINGS, 2010, 42 (07) :2650-2652
12345