A collision tumor of solitary fibrous tumor/hemangiopericytoma and meningioma: A case report with literature review

被引：6

作者：

Ashizawa, Karin ^{[1
]}

Ogura, Kanako ^{[1
]}

Nagase, Shunsuke ^{[2
]}

Sakaguchi, Asumi ^{[1
]}

Tokugawa, Joji ^{[3
]}

Hishii, Makoto ^{[3
]}

Fukunaga, Masaharu ^{[4
]}

Hirose, Takanori ^{[5
,6
]}

Matsumoto, Toshiharu ^{[1
]}

机构：

[1] Juntendo Univ, Nerima Hosp, Dept Diagnost Pathol, 3-1-10 Takanodai, Nerima, Tokyo 1778521, Japan

[2] Juntendo Univ, Dept Human Pathol, Sch Med, Tokyo, Japan

[3] Juntendo Univ, Nerima Hosp, Dept Neurosurg, Tokyo, Japan

[4] Shin Yurigaoka Gen Hosp, Dept Pathol, Kawasaki, Kanagawa, Japan

[5] Hyogo Canc Ctr, Dept Diagnost Pathol, Akashi, Hyogo, Japan

[6] Kobe Univ, Sch Med, Div Pathol Reg Commun, Akashi, Hyogo, Japan

来源：

PATHOLOGY INTERNATIONAL | 2021年 / 71卷 / 10期

关键词：

collision tumor; meningioma; solitary fibrous tumor; hemangiopericytoma (SFT; HPC); STAT6; CENTRAL-NERVOUS-SYSTEM; GLIOBLASTOMA-MULTIFORME; PITUITARY-ADENOMA; MENINGEAL HEMANGIOPERICYTOMA; DIFFERENTIAL-DIAGNOSIS; VESTIBULAR SCHWANNOMA; COEXISTENCE; LYMPHOMA; GLIOMA;

D O I：

10.1111/pin.13150

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

An intracranial collision tumor is a rare lesion composed of two histologically different neoplasms in the same anatomic location. Even more rare is the collision tumor of a solitary fibrous tumor/hemangiopericytoma (SFT/HPC) and meningioma. The patient was a 46-year-old woman who had a 40 x 35 x 30-mm mass in the vermis of the cerebellum. Histologically, the mass consisted of two different components. One component showed the morphology of meningioma (World Health Organization (WHO) grade I), and the other component exhibited small round cell proliferation with hypercellular density, which was revealed to be SFT/HPC (WHO grade III) based on STAT6 immunohistochemistry. STAT6 showed completely different immunohistochemistry results in these two components (nuclear-negative in meningioma and nuclear-positive in SFT/HPC). Since these two neoplasms are associated with different prognoses, they should be distinguished from each other. When meningioma and an SFT/HPC-like lesion are identified morphologically, it is important to recognize the presence of such a collision tumor composed of meningioma and SFT/HPC, and identify the SFT/HPC component by employing STAT6 immunohistochemistry.

引用

页码：697 / 706

页数：10

共 49 条

[1]

Amirjamshidi A, 2017, J SURG CASE REP, DOI 10.1093/jscr/rjx039

[2] Hemangiopericytoma: collision with meningioma and recurrence [J].