The Hyperpolarization-Activated Cation Current Ih: The Missing Link Connecting Cannabinoids to Cognition

被引：4
|
作者：
Vargish, Geoffrey A. [1 ]
McBain, Chris J. [1 ]
机构：
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Dev Neurobiol, NIH, Bethesda, MD 20892 USA
来源：
NEURON | 2016年 / 89卷 / 05期
关键词：
CELLS;
D O I：
10.1016/j.neuron.2016.02.027
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
In this issue of Neuron, Maroso et al. (2016) describe a novel link between cannabinoids and cognition. They show that CB1Rs bidirectionally modulate HCN-mediated Ih in a subset of CA1 pyramidal neurons to influence both short- and long-term circuit dynamics and alter spatial working memory in behaving mice.
引用
收藏
页码：889 / 891
页数：3
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