The Effects of Cloudberry Fruit Extract on Drosophila melanogaster Lifespan and Stress Resistance

被引:5
作者
Lashmanova, E. A. [1 ,2 ]
Kuzivanova, O. A. [1 ]
Dymova, O., V [1 ]
Moskalev, A. A. [1 ,2 ,3 ,4 ]
机构
[1] Russian Acad Sci, Komi Sci Ctr, Inst Biol, Ural Branch, Syktyvkar 167982, Russia
[2] Moscow Inst Phys & Technol, Dolgoprudnyi 141701, Moscow Oblast, Russia
[3] Pitirim Sorokin Syktyvkar State Univ, Syktyvkar 167001, Russia
[4] Russian Acad Sci, Vavilov Inst Gen Genet, Moscow 119991, Russia
关键词
cloudberry; lifespan; stress resistance; Drosophila melanogaster; EXTENSION; LONGEVITY; CALORIES;
D O I
10.1134/S2079057019020127
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
We previously demonstrated that carotenoids increase the lifespan of model organisms Drosophila melanogaster and Caenorhabditis elegans. This work studies the effect of the extract of cloudberry fruits (which is characterized by a relatively high content of carotenoids and widely used for food in the north) on lifespan parameters and resistance to various types of stress in the Drosophila melanogaster flies. It is demonstrated that cloudberry extract increased median lifespan and the age of 90% mortality in females up to 11-19%, and it decreased the population aging rate in them by 13%. At the same time, the effect of the cloudberry fruit extract on the lifespan of males was weakly pronounced (and was negative in some cases). The extract did not affect the resistance of Drosophila males and females to starvation and decreased the resistance of males to oxidative stress.
引用
收藏
页码:254 / 260
页数:7
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