Probing structural changes of self assembled i-motif DNA

被引：53
作者：
Lee, Il Joon [1 ]
Patil, Sachin P. [1 ]
Fhayli, Karim [1 ]
Alsaiari, Shahad [1 ]
Khashab, Niveen M. [1 ]
机构：
[1] KAUST, Adv Membranes & Porous Mat Ctr, Controlled Release & Delivery Lab CRD, Thuwal 239556900, Makkah, Saudi Arabia
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 18期
关键词：
THIOFLAVIN-T; G-QUADRUPLEX; LOGIC GATES; LABEL-FREE; SELECTIVE RECOGNITION; GENE-EXPRESSION; FLUORESCENCE; MECHANISM; SENSOR; NANOPARTICLES;
D O I：
10.1039/c4cc06824f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report an i-motif structural probing system based on Thioflavin T (ThT) as a fluorescent sensor. This probe can discriminate the structural changes of RET and Rb i-motif sequences according to pH change.
引用
收藏
页码：3747 / 3749
页数：3
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  • [1] Molecular Rotors: What Lies Behind the High Sensitivity of the Thioflavin-T Fluorescent Marker
    Amdursky, Nadav
    Erez, Yuval
    Huppert, Dan
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 2012, 45 (09) : 1548 - 1557
  • [2] Thioflavin T forms a non-fluorescent complex with α-helical poly-L-glutamic acid
    Babenko, Viktoria
    Dzwolak, Wojciech
    [J]. CHEMICAL COMMUNICATIONS, 2011, 47 (38) : 10686 - 10688
  • [3] Molecular Mechanism of Thioflavin-T Binding to the Surface of β-Rich Peptide Self-Assemblies
    Biancalana, Matthew
    Makabe, Koki
    Koide, Akiko
    Koide, Shohei
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2009, 385 (04) : 1052 - 1063
  • [4] Making sense of G-quadruplex and i-motif functions in oncogene promoters
    Brooks, Tracy A.
    Kendrick, Samantha
    Hurley, Laurence
    [J]. FEBS JOURNAL, 2010, 277 (17) : 3459 - 3469
  • [5] The poly dA helix: a new structural motif for high performance DNA-based molecular switches
    Chakraborty, Saikat
    Sharma, Suruchi
    Maiti, Prabal K.
    Krishnan, Yamuna
    [J]. NUCLEIC ACIDS RESEARCH, 2009, 37 (09) : 2810 - 2817
  • [6] SYNTHESIS FROM DNA OF A MOLECULE WITH THE CONNECTIVITY OF A CUBE
    CHEN, JH
    SEEMAN, NC
    [J]. NATURE, 1991, 350 (6319) : 631 - 633
  • [7] Label-free fluorescent bio sensor based on the target recycling and Thioflavin T-induced quadruplex formation for short DNA species of c-erbB-2 detection
    Chen, Jinghua
    Lin, Jia
    Zhang, Xi
    Cai, Shuxian
    Wu, Dongzhi
    Li, Chunyan
    Yang, Sheng
    Zhang, Jing
    [J]. ANALYTICA CHIMICA ACTA, 2014, 817 : 42 - 47
  • [8] Construction of molecular logic gates with a DNA-cleaving deoxyribozyme
    Chen, X
    Wang, YF
    Liu, Q
    Zhang, ZZ
    Fan, CH
    He, L
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (11) : 1759 - 1762
  • [9] A pH-Triggered, Fast-Responding DNA Hydrogel
    Cheng, Enjun
    Xing, Yongzheng
    Chen, Ping
    Yang, Yang
    Sun, Yawei
    Zhou, Dejian
    Xu, Lijin
    Fan, Qinghua
    Liu, Dongsheng
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (41) : 7660 - 7663
  • [10] Conformational changes of non-B DNA
    Choi, Jungkweon
    Majima, Tetsuro
    [J]. CHEMICAL SOCIETY REVIEWS, 2011, 40 (12) : 5893 - 5909
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