Catalytic asymmetric epoxidation of α,β-unsaturated esters using an yttrium-biphenyidiol complex

被引：65

作者：

Kakei, H ^{[1
]}

Tsuji, R ^{[1
]}

Ohshima, T ^{[1
]}

Shibasaki, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 25期

关键词：

D O I：

10.1021/ja052466t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We succeeded in a catalytic asymmetric epoxidation reaction of α,β-unsaturated esters via a conjugate addition of an oxidant using 2-10 mol % of the yttirium-chiral biphenyldiol catalyst. A variety of substrates with β-aryl and β-alkyl substituents were epoxidized efficiently, yielding the corresponding α,β-epoxy esters in up to 97% yield and 99% ee. Copyright © 2005 American Chemical Society.

引用

页码：8962 / 8963

页数：2

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