Pyrrolizidine and tetrahydroisoquinoline alkaloids from Echium humile

被引:26
作者
ElShazly, A
Sarg, T
Ateya, A
Aziz, EA
ElDahmy, S
Witte, L
Wink, M
机构
[1] TECH UNIV CAROLO WILHELMINA BRAUNSCHWEIG,INST PHARMAZEUT BIOL,D-38106 BRAUNSCHWEIG,GERMANY
[2] UNIV HEIDELBERG,INST PHARMAZEUT BIOL,D-69120 HEIDELBERG,GERMANY
关键词
Echium humile; Boraginaceae; pyrrolizidine alkaloids; echihumiline; pycnanthine; echihumiline N-oxide; 7-; and; 9-senecioylretronecine; lycopsamine; 7-acetyl-lycopsamine; tetrahydro-isoquinoline; carnegine;
D O I
10.1016/0031-9422(95)00847-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three new pyrrolizidine alkaloids, echilumiline, pycananthine and echihumiline N-oxide, were isolated from Echium humile and their structures determined by spectroscopic methods. In addition, we record the presence of the known alkaloids, 7-senecioylretronecine, 9-senecioylretronecine, lycopsamine and 7-acetyl-lycopsamine. The tetrahydro-isoquinoline alkaloid, carnegine, was reduced for the first time in the Boraginaceae.
引用
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页码:225 / 230
页数:6
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