A rhodamine-based fluorescent probe containing a Se-N bond for detecting thiols and its application in living cells

被引:397
作者
Tang, Bo [1 ]
Xing, Yanlong
Li, Ping
Zhang, Ning
Yu, Fabiao
Yang, Guiwen
机构
[1] Shandong Normal Univ, Coll Med, Engn Res Ctr Pesticide & Med Intermediate, Minist Educ, Jinan 250014, Peoples R China
[2] Shandong Normal Univ, Coll Life Sci, Jinan 250014, Peoples R China
关键词
D O I
10.1021/ja072572q
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Here we report a new rhodamine-based fluorescent probe containing a selenium-nitrogen bond for detecting thiols based on the nucleophilic substitution of sulfhydryl. The probe was successfully applied to the imaging of thiols in both HL-7702 cells and HepG2 cells with high sensitivity and selectivity.
引用
收藏
页码:11666 / +
页数:3
相关论文
共 33 条