Applied Biotransformations in Green Solvents

被引:94
作者
Hernaiz, Maria J. [1 ,2 ]
Alcantara, Andres R. [1 ]
Garcia, Jose I. [4 ]
Sinisterra, Jose V. [1 ,3 ]
机构
[1] Univ Complutense Madrid, Fac Farm, Grp Biotransformac, Dept Quim Organ & Farmaceut, E-28040 Madrid, Spain
[2] Univ Complutense Madrid, Fac Farm, Serv Interacc Mol, E-28040 Madrid, Spain
[3] Serv Biotransformac Ind, Madrid 28760, Spain
[4] Univ Zaragoza, CSIC, Fac Ciencias, Dept Quim Organ,Inst Ciencias Mat Aragon, E-50009 Zaragoza, Spain
关键词
biocatalysts; biotransformations; green chemistry; sustainable chemistry; white biotechnology; SUPERCRITICAL CARBON-DIOXIDE; DYNAMIC KINETIC RESOLUTION; BIOCATALYTIC KETONE REDUCTION; SUSTAINABLE ORGANIC-SYNTHESIS; WHOLE-CELL BIOCATALYSIS; IONIC LIQUIDS; ENZYMATIC-REACTIONS; ASYMMETRIC REDUCTION; EFFICIENT SYNTHESIS; DIRECTED EVOLUTION;
D O I
10.1002/chem.201000798
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The definite interest in implementing sustainable industrial technologies has impelled the use of biocatalysts (enzymes or cells), leading to high chemo-, regio- and stereoselectivities under mild conditions. As usual substrates are not soluble in water, the employ of organic solvents is mandatory. We will focus on different attempts to combine the valuable properties of green solvents with the advantages of using biocatalysts for developing cleaner synthetic processes.
引用
收藏
页码:9422 / 9437
页数:16
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