Examining the effect of regioisomerism on the physico-chemical properties of lysophosphatidylethanolamine-containing liposomes using fluoro probes

被引：0
|
作者：
Yamamoto, Yusuke [1 ]
Furukawa, Takayuki [1 ]
Takeda, Seiji [1 ]
Kashida, Hiroyuki [1 ]
Chiba, Hitoshi [1 ]
Hui, Shu-Ping [1 ]
机构：
[1] Hokkaido Univ, Grad Sch Hlth Sci, Kita Ku, North 12,West 5, Sapporo, Hokkaido 0600812, Japan
来源：
CHEMISTRY AND PHYSICS OF LIPIDS | 2018年 / 216卷
关键词：
Lysophosphatidylethanolamine; Acyl migration; Fluoro analogue; Chemical synthesis; Phase-transition temperature; DIFFERENTIAL SCANNING CALORIMETRY; POLYMORPHIC PHASE-BEHAVIOR; ANALOGS; LYSOPHOSPHATIDYLSERINE; CURVATURE; RECEPTORS; MODEL;
D O I：
10.1016/j.chemphyslip.2018.08.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Lysophospholipids (LysoPLs) receive steadily increasing attention in the area of lipid chemistry and biology. However, the physico-chemical properties of individual LysoPL regioisomers have not yet been investigated. Herein, we report the synthesis of fluoro analogues of lysophosphatidylethanolamines (LPEs) and examine the physico-chemical properties of the LPE regioisomers using chemically synthesized fluoro probes.
引用
收藏
页码：9 / 16
页数：8
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