Protein S-100B, neuron-specific enolase (NSE), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and blood of neurological patients

被引：112

作者：

Lamers, KJB

Vos, P

Verbeek, MM

Rosmalen, F

van Geel, WJA

van Engelen, BGM

机构：

[1] Univ Nijmegen, Med Ctr, Lab Pediat & Neurol, NL-6500 HB Nijmegen, Netherlands

[2] Univ Nijmegen, Med Ctr, Inst Neurol, NL-6500 HB Nijmegen, Netherlands

[3] Future Diagnost, Wychen, Netherlands

来源：

BRAIN RESEARCH BULLETIN | 2003年 / 61卷 / 03期

关键词：

acute brain damage; brain-specific proteins; human body fluids;

D O I：

10.1016/S0361-9230(03)00089-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this study, data about protein S-100B, neuron-specific enolase, myelin basic protein and glial fibrillary acidic protein in cerebrospinal fluid and blood of patients with an acute or chronic progressive neurological disorder with brain damage are reviewed. Especially in disorders with acute brain damage, determination of these proteins in CSF and blood can be helpful to establish structural and/or functional brain damage to determine severity and prognosis of the disease process and to monitor treatment effects. (C) 2003 Elsevier Science Inc. All rights reserved.

引用

页码：261 / 264

页数：4