Preparation of N-Boc-(2,6-bis-(ethoxycarbonyl)pyridin-4-yl)-L-alanines as tridentate ligands

被引：21

作者：

Schmidt, B ^{[1
]}

Ehlert, DK ^{[1
]}

机构：

[1] Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 23期

关键词：

pyridine; tridentate ligand; Heck olefination; lanthanide; zinc mediated addition;

D O I：

10.1016/S0040-4039(98)00711-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The pyridylalanine 7a was synthesised in good yield from serine and 4-bromopyridine 3. The pyridylpropionates 12, 13 were synthesised in good yields by either Heckolefination or palladium catalysed cross coupling. (C) 1998 Elsevier Science Ltd. Ail rights reserved.

引用

页码：3999 / 4002

页数：4

共 15 条

[1]

ACHYUTHARAO S, 1991, J ORG CHEM, V56, P4591

[2] NUCLEAR ANALOGS OF BETA-LACTAM ANTIBIOTICS .2. TOTAL SYNTHESIS OF 8-OXO-4-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACIDS [J].

BRYAN, DB ;

HALL, RF ;

HOLDEN, KG ;

HUFFMAN, WF ;

GLEASON, JG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (07) :2353-2355

[3] Functional models for vanadium haloperoxidase: Reactivity and mechanism of halide oxidation [J].

Colpas, GJ ;

Hamstra, BJ ;

Kampf, JW ;

Pecoraro, VL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (14) :3469-3478

[4]

DUNN MJ, 1993, SYNLETT, P499

[5] (S)-ALPHA-AMINO-2,2'-BIPYRIDINE-6-PROPANOIC ACID - A VERSATILE AMINO-ACID FOR DENOVO METALLOPROTEIN DESIGN [J].

IMPERIALI, B ;

FISHER, SL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (22) :8527-8528

[6] CARBONYLATIVE COUPLING OF AN AMINO ACID-DERIVED ORGANOZINC REAGENT WITH FUNCTIONALIZED ARYL IODIDES - SYNTHESIS OF KYNURENINE [J].

JACKSON, RFW ;

TURNER, D ;

BLOCK, MH .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (21) :2207-2208

[7] Carbonylative coupling of organozinc reagents in the presence and absence of aryl iodides: Synthesis of unsymmetrical and symmetrical ketones [J].

Jackson, RFW ;

Turner, D ;

Block, MH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1997, (06) :865-870

[8]

LINDEBERG G, 1991, INT J PEPT PROT RES, V38, P253

[9]

Neidleman SL., 1986, BIOHALOGENATION PRIN

[10] DNA BENDING AND BINDING BY METALLO-ZIPPER MODELS OF BZIP PROTEINS [J].

PALMER, CR ;

SLOAN, LS ;

ADRIAN, JC ;

CUENOUD, B ;

PAOLELLA, DN ;

SCHEPARTZ, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (35) :8899-8907

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