Strategies to increase the donor pool and access to kidney transplantation: an international perspective

被引:67
作者
Maggiore, Umberto [1 ]
Oberbauer, Rainer [2 ,3 ]
Pascual, Julio [4 ]
Viklicky, Ondrej [5 ]
Dudley, Chris [6 ]
Budde, Klemens [7 ]
Sorensen, Soren Schwartz [8 ]
Hazzan, Marc [9 ]
Klinger, Marian [10 ]
Abramowicz, Daniel [11 ]
机构
[1] Azienda Osped Univ Parma, Dept Nephrol, Parma, Italy
[2] Med Univ Vienna, KH Elisabethinen Linz, Vienna, Austria
[3] Med Univ Vienna, Dept Nephrol, Vienna, Austria
[4] Hosp del Mar, Dept Nephrol, Barcelona, Spain
[5] Inst Clin & Expt Med, Dept Nephrol, Prague, Czech Republic
[6] Richard Bright Renal Unit, Bristol, Avon, England
[7] Charite, Dept Nephrol, D-13353 Berlin, Germany
[8] Univ Copenhagen, Rigshosp, Dept Nephrol P, DK-2100 Copenhagen, Denmark
[9] Univ Lille Nord France, Serv Nephrol, Lille, France
[10] Wroclaw Med Univ, Dept Nephrol & Transplantat Med, Wroclaw, Poland
[11] Univ Antwerp Hosp, Dept Nephrol, Antwerp, Belgium
关键词
antibody-incompatible kidney transplantation; donation after circulatory death; kidney transplantation; marginal donor; paired donation; HIGHLY SENSITIZED PATIENTS; INCOMPATIBLE RENAL-TRANSPLANTATION; ACCEPTABLE MISMATCH PROGRAM; PAIRED DONATION; INTRAVENOUS IMMUNOGLOBULIN; DESENSITIZATION; HLA; IMMUNOADSORPTION; ALLOCATION; RECIPIENTS;
D O I
10.1093/ndt/gfu212
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
In this position article, DESCARTES (Developing Education Science and Care for Renal Transplantation in European States) board members describe the current strategies aimed at expanding living and deceased donor kidney pools. The article focuses on the recent progress in desensitization and kidney paired exchange programmes and on the expanded criteria for the use of donor kidneys and organs from donors after circulatory death. It also highlights differences in policies and practices across different regions with special regard to European Union countries. Living donor kidney paired exchange, the deceased donor Acceptable Mismatch Programme and kidneys from donors after circulatory death are probably the most promising innovations for expanding kidney transplantation in Europe over the coming decade. To maximize success, an effort is needed to standardize transplant strategies, policies and legislation across European countries.
引用
收藏
页码:217 / 222
页数:7
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