Hematopoietic stem cell transplantation for systemic lupus erythematosus

被引：10

作者：

Burt, RK ^{[1
]}

Traynor, AE ^{[1
]}

机构：

[1] Northwestern Univ, Sch Med, Div Immunotherapy, Chicago, IL 60611 USA

来源：

ARTHRITIS RESEARCH & THERAPY | 2003年 / 5卷 / 05期

关键词：

hematopoietic stem cell transplantation; lupus;

D O I：

10.1186/ar786

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hematopoietic stem cell transplantation was first reported for patients with systemic lupus erythematosus in 1997. The procedure has since been performed worldwide including in Europe, in Brazil, and in China. A National Institutes of Health-funded phase III clinical trial of hematopoietic stem cell transplantation for refractory systemic lupus erythematosus is anticipated to begin in 2003. Encouraging responses are raising new hope about the role of adult hematopoietic stem cells in systemic lupus erythematosus.

引用

页码：207 / 209

页数：3

共 15 条

[1] A DIFFERENTIAL-AVIDITY MODEL FOR T-CELL SELECTION [J].

ASHTONRICKARDT, PG ;

TONEGAWA, S .

IMMUNOLOGY TODAY, 1994, 15 (08) :362-366

[2] SELECTING THE T-CELL RECEPTOR REPERTOIRE [J].

BEVAN, MJ ;

HOGQUIST, KA ;

JAMESON, SC .

SCIENCE, 1994, 264 (5160) :796-797

[3] Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease [J].

Brodsky, RA ;

Petri, M ;

Smith, BD ;

Seifter, EJ ;

Spivak, JL ;

Styler, M ;

Dang, CV ;

Brodsky, I ;

Jones, RJ .

ANNALS OF INTERNAL MEDICINE, 1998, 129 (12) :1031-1035

[4]

Burt RK, 1999, ARTHRITIS RHEUM, V42, P2281, DOI 10.1002/1529-0131(199911)42:11<2281::AID-ANR4>3.0.CO

[5]

2-E

[6] Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure? [J].

Burt, RK ;

Slavin, S ;

Burns, WH ;

Marmont, AM .

BLOOD, 2002, 99 (03) :768-784

[7] Hematopoietic stem-cell transplantation for systemic lupus erythematosus [J].

Burt, RK ;

Traynor, A ;

RamseyGoldman, R .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (24) :1777-1778

[8] Autologous marrow stem cell transplantation for severe systemic lupus erythematosus of long duration [J].

Marmont, AM ;

vanLint, MT ;

Gualandi, F ;

Bacigalupo, A .

LUPUS, 1997, 6 (06) :545-548

[9] High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes [J].

McSweeney, PA ;

Nash, RA ;

Sullivan, KM ;

Storek, J ;

Crofford, LJ ;

Dansey, R ;

Mayes, MD ;

McDonagh, K ;

Nelson, JL ;

Gooley, TA ;

Holmberg, LA ;

Chen, CS ;

Wener, MH ;

Ryan, K ;

Sunderhaus, J ;

Russell, K ;

Rambharose, J ;

Storb, R ;

Furst, DE .

BLOOD, 2002, 100 (05) :1602-1610

[10] A pilot randomized trial comparing CD34-selected versus unmanipulated hemopoietic stem cell transplantation for severe, refractory rheumatoid arthritis [J].

Moore, J ;

Brooks, P ;

Milliken, S ;

Biggs, J ;

Ma, D ;

Handel, M ;

Cannell, P ;

Will, R ;

Rule, S ;

Joske, D ;

Langlands, B ;

Taylor, K ;

O'Callaghan, J ;

Szer, J ;

Wicks, I ;

McColl, G ;

Passeullo, F ;

Snowden, J .

ARTHRITIS AND RHEUMATISM, 2002, 46 (09) :2301-2309

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