TOWARDS IMAGING SKIN CANCER BY APERTURELESS SCANNING NEAR-FIELD OPTICAL MICROSCOPY

被引:0
|
作者
Stanciu, Stefan G. [1 ]
Costache, Mariana [2 ]
Tranca, Denis E. [1 ]
Hristu, Radu [1 ]
Popescu, Marius [1 ,3 ]
Enache, Valentin [3 ]
Stanciu, George A. [1 ]
机构
[1] Univ Politehn Bucuresti, Ctr Microscopy Microanal & Informat Proc, Splaiul Independentei 313, Bucharest, Romania
[2] Carol Davila Univ Med & Pharm, Eroii Sanitari 8, Bucharest, Romania
[3] Clin Emergency Hosp Bucharest, Calea Floreasca 8, Bucharest, Romania
来源
UNIVERSITY POLITEHNICA OF BUCHAREST SCIENTIFIC BULLETIN-SERIES A-APPLIED MATHEMATICS AND PHYSICS | 2016年 / 78卷 / 02期
关键词
ASNOM; CLSM; skin cancer; squamous cell carcinoma; microscopy; nanoscopy; MORPHOLOGIC FEATURES;
D O I
暂无
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Laser Scanning Microscopy Techniques such as Confocal Microscopy, Two Photon Excitation Microscopy, Second Harmonic Generation Microscopy or Fluorescence Lifetime Imaging have been successfully employed to date for imaging skin cancer. However, the resolution that such techniques can provide is limited by diffraction, which prevents accurately imaging (and differentiating) optical details sized below similar to 200nm, which could potentially advance our current understanding of skin cancer progression or causes. In this paper we present the results of our first efforts on imaging tissue samples relevant for skin cancer research at optical resolutions beyond the diffraction limit by using Apertureless Scanning Near-Field Optical Microscopy.
引用
收藏
页码:235 / 244
页数:10
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