Review: Vaccines and Vaccination against Lumpy Skin Disease

被引：108

作者：

Tuppurainen, Eeva ^{[1
]}

Dietze, Klaas ^{[1
]}

Wolff, Janika ^{[2
]}

Bergmann, Hannes ^{[3
]}

Beltran-Alcrudo, Daniel ^{[4
]}

Fahrion, Anna ^{[1
]}

Lamien, Charles Euloge ^{[5
]}

Busch, Frank ^{[1
]}

Sauter-Louis, Carola ^{[3
]}

Conraths, Franz J. ^{[3
]}

De Clercq, Kris ^{[6
]}

Hoffmann, Bernd ^{[2
]}

Knauf, Sascha ^{[1
]}

机构：

[1] Friedrich Loeffler Inst, Fed Res Inst Anim Hlth, Inst Int Anim Hlth Hlth 1, Sudufer 10, D-17493 Greifswald, Germany

[2] Friedrich Loeffler Inst, Fed Res Inst Anim Hlth, Inst Diagnost Virol, Sudufer 10, D-17493 Greifswald, Germany

[3] Friedrich Loeffler Inst, Fed Res Inst Anim Hlth, Inst Epidemiol, Sudufer 10, D-17493 Greifswald, Germany

[4] Food & Agr Org, Reg Off Europe & Cent Asia, 20 Kalman Imre Utca, H-1054 Budapest, Hungary

[5] Int Atom Energy Agcy IAEA, Dept Nucl Sci & Applicat, FAO IAEA Div Nucl Tech Food & Agr, Friedenstr 1, A-2444 Seibersdorf, Austria

[6] Sciensano, Sci Directorate Infect Dis Anim, Unit Exot & Particular Dis, Groeselenberg 99, B-1180 Brussels, Belgium

来源：

VACCINES | 2021年 / 9卷 / 10期

关键词：

capripoxvirus; lumpy skin disease; cattle; LSD; immunization; vaccination; MECHANICAL TRANSMISSION; MAMMALIAN POXVIRUSES; VIRUS; CAPRIPOXVIRUS; CATTLE; SHEEP; FIELD; OUTBREAKS; EFFICACY; STRAIN;

D O I：

10.3390/vaccines9101136

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The geographical distribution of lumpy skin disease (LSD), an economically important cattle disease caused by a capripoxvirus, has reached an unprecedented extent. Vaccination is the only way to prevent the spread of the infection in endemic and newly affected regions. Yet, in the event of an outbreak, selection of the best vaccine is a major challenge for veterinary authorities and farmers. Decision makers need sound scientific information to support their decisions and subsequent actions. The available vaccine products vary in terms of quality, efficacy, safety, side effects, and price. The pros and cons of different types of live attenuated and inactivated vaccines, vaccination strategies, and associated risks are discussed. Seroconversion, which typically follows vaccination, places specific demands on the tools and methods used to evaluate the effectiveness of the LSD vaccination campaigns in the field. We aimed to give a comprehensive update on available vaccines and vaccination against LSD, to better prepare affected and at-risk countries to control LSD and ensure the safe trade of cattle.

引用

页数：22

共 137 条

[1] Sporadic cases of lumpy skin disease among cattle in Sharkia province, Egypt: Genetic characterization of lumpy skin disease virus isolates and pathological findings [J].