Clinicopathologic and molecular features of Hodgkin's lymphoma

被引：8
作者：
Younes, A
Carbone, A
机构：
[1] Univ Texas, MD Anderson Canc Ctr, Dept Lymphoma Myeloma, Houston, TX 77030 USA
[2] IRCCS, Ist Nazl Tumori, Ctr Riferimento Oncol, Div Pathol, Aviano, Italy
来源：
CANCER BIOLOGY & THERAPY | 2003年 / 2卷 / 05期
关键词：
Reed-Sternberg; cytokines; NF-kappa B; ERK; CD30; CD40; RANK; TRAIL; Rituximab;
D O I：
10.4161/cbt.2.5.510
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Hodgkin's lymphoma is a relatively uncommon malignancy that predominantly effects young adults. It became the first human cancer to be cured with combination chemotherapy. Unfortunately, many cured patients do not live their expected lifespan because of long-term lethal effects of therapy. Novel treatment strategies based on our understanding of Hodgkin's lymphoma biology are currently being explored to maintain the high cure rate without the added treatment related toxicity.
引用
收藏
页码：500 / 507
页数：8
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