EROD activity in liver and gills of polar cod (Boreogadus saida) exposed to waterborne and dietary crude oil

被引：22

作者：

Nahrgang, Jasmine ^{[1
,2
]}

Jonsson, Martina ^{[1
,2
]}

Camus, Lionel ^{[1
]}

机构：

[1] Polar Environm Ctr, N-9296 Tromso, Norway

[2] Univ Tromso, Dept Arctic & Marine BioSci, N-9037 Tromso, Norway

来源：

MARINE ENVIRONMENTAL RESEARCH | 2010年 / 70卷 / 01期

关键词：

Crude oil; EROD activity; Polar cod; Arctic; Gills; Liver; FISH;

D O I：

10.1016/j.marenvres.2010.02.003

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Polar cod Boreogadus saida an indicator species for biomonitoring in the Arctic was exposed to crude oil in waterborne and dietary experiments Ethoxyresorufin O-deethylase (EROD) activity was measured in liver and gills of polar cod at weeks 0, 2 and 4 of exposure and following 2 weeks of depuration. EROD increased significantly and dose-dependently in both tissues through both exposure routes. Levels were very low in gills compared to liver reflecting the tissue-specific metabolism capacities and tissue-specific response kinetics were also observed Furthermore, a significant Increase of gill EROD was shown in dietary exposed fish, demonstrating a substantial transport of PAHs via the systemic circulation To conclude, this study gave some preliminary information on the EROD response in terms of levels, dose dependency and timing, in gills of PAH exposed polar cod (C) 2010 Elsevier Ltd. All rights reserved

引用

页码：120 / 123

页数：4

共 14 条

[1] Effects of 17α-ethynylestradiol on EROD activity, spiggin and vitellogenin in three-spined stickleback (Gasterosteus aculeatus) [J].

Andersson, Carin ;

Katsiadaki, Ioanna ;

Lundstedt-Enkel, Katrin ;

Orberg, Jan .

AQUATIC TOXICOLOGY, 2007, 83 (01) :33-42

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] Sensitivity of fish embryos to weathered crude oil:: Part I.: Low-level exposure during incubation causes malformations, genetic damage, and mortality in larval Pacific herring (Clupea pallasi) [J].

Carls, MG ;

Rice, SD ;

Hose, JE .

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 1999, 18 (03) :481-493

[4] ETHOXYRESORUFIN-O-DEETHYLASE (EROD) ACTIVITY IN FLATFISH - FAST DETERMINATION WITH A FLUORESCENCE PLATE-READER [J].

EGGENS, ML ;

GALGANI, F .

MARINE ENVIRONMENTAL RESEARCH, 1992, 33 (03) :213-221

[5]

Hinton David E., 2008, P327, DOI 10.1201/9780203647295.ch7

[6] Water column monitoring near oil installations in the North Sea 2001-2004 [J].

Hylland, Ketil ;

Tollefsen, Knut-Erik ;

Ruus, Anders ;

Jonsson, Grete ;

Sundt, Rolf C. ;

Sanni, Steinar ;

Utvik, Toril Inga Roe ;

Johnsen, Stale ;

Nilssen, Ingunn ;

Pinturier, Laurence ;

Balk, Lennart ;

Barsiene, Janina ;

Marigomez, Ionan ;

Feist, Stephen W. ;

Borseth, Jan Fredrik .

MARINE POLLUTION BULLETIN, 2008, 56 (03) :414-429

[7]

*JAMP, 1998, JOINT ASS MON PROGR

[8] Gill filament-based EROD assay for monitoring waterborne dioxin-like pollutants in fish [J].

Jönsson, EM ;

Brandt, I ;

Brunström, B .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2002, 36 (15) :3340-3344

[9] The zebrafish gill model: Induction of CYP1A, EROD and PAH adduct formation [J].

Jonsson, Maria E. ;

Brunstrom, Bjorn ;

Brandt, Ingvar .

AQUATIC TOXICOLOGY, 2009, 91 (01) :62-70

[10] Biomarker responses in polar cod (Boreogadus saida) exposed to the water soluble fraction of crude oil [J].

Nahrgang, Jasmine ;

Camus, Lionel ;

Carls, Mark G. ;

Gonzalez, Patrice ;

Jonsson, Martina ;

Taban, Ingrid C. ;

Bechmann, Renee K. ;

Christiansen, Jorgen S. ;

Hop, Haakon .

AQUATIC TOXICOLOGY, 2010, 97 (03) :234-242

← 1 2 →