Microwave-induced one-pot synthesis of 4-[3-(aryl)-1,2,4-oxadiazol-5-yl]-butan-2-ones under solvent free conditions

被引：36
作者：
de Freitas, Juclelton Jose R.
de Freitas, Juliano Carlo R.
da Silva, Ladjane P.
de Freitas, Joao R. [1 ]
Kimura, Gisele Y. V.
Srivastava, Rajendra M.
机构：
[1] Univ Fed Pernambuco, Dept Quim Fundamental, BR-50074054 Recife, PE, Brazil
[2] Univ Fed Rural Pernambuco, Unidade Acad Garanhuns, Recife, PE, Brazil
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 35期
关键词：
D O I：
10.1016/j.tetlet.2007.06.116
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of 4-[3-(aryl)-1,2,4-oxadiazol-5-yl]-butan-2-ones (5a-I) from methyl levulinate (4) and arylamidoximes (1a-I) is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in yields comparable with conventional heating. (C) 2007 Elsevier Ltd. All rights reserved.
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页码：6195 / 6198
页数：4
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