Finite element modeling of cooled-tip probe radiofrequency ablation processes in liver tissue

被引：43

作者：

Barauskas, Rimantas ^{[2
]}

Gulbinas, Antanas ^{[3
]}

Vanagas, Tomas ^{[1
]}

Barauskas, Giedrius ^{[1
]}

机构：

[1] Kaunas Univ Med, Dept Surg, LT-50009 Kaunas, Lithuania

[2] Kaunas Univ Technology, Dept Syst Anal, Kaunas, Lithuania

[3] Kaunas Univ Med, Inst Biomed Res, LT-50009 Kaunas, Lithuania

来源：

COMPUTERS IN BIOLOGY AND MEDICINE | 2008年 / 38卷 / 06期

关键词：

radiofrequency ablation; computational modeling; hydraulic conductivity; experimental research;

D O I：

10.1016/j.compbiomed.2008.03.007

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Finite element model of radiofrequency ablation (RFA) with cooled-tip probe in liver has been developed by employing COMSOL Multiphysics software. It describes coupled electric, thermal and sodium chloride solution infiltration flow phenomena taking place during ablation processes. Features of hydraulic capacity, saturation of the tissue by infiltration, and dependency of electrical conductivity on the damage integral of the tissue have been supplied to the model. RFA experiments have validated the model. Physical parameters describing hydraulic capacity and hydraulic conductivity in the tissue, as well as, the relation of electrical conductivity against the value of damage integral have been determined. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：694 / 708

页数：15

共 17 条

[1] RATE-PROCESS MODEL FOR ARTERIAL TISSUE THERMAL-DAMAGE - IMPLICATIONS ON VESSEL PHOTOCOAGULATION [J].