Treatment of Histologic Transformation

被引:6
作者
Casulo, Carla [1 ]
机构
[1] Wilmot Canc Inst, Med & Oncol, 601 Elmwood Ave Box 704, Rochester, NY 14642 USA
关键词
Follicular lymphoma; Transformed lymphoma; Histologic transformation; Therapy; Prognosis; NON-HODGKIN-LYMPHOMA; B-CELL LYMPHOMA; FOLLICULAR LYMPHOMA; 1ST-LINE TREATMENT; PLUS RITUXIMAB; RISK-FACTORS; INDOLENT; SURVIVAL; OUTCOMES; ERA;
D O I
10.1016/j.hoc.2020.03.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Histologic transformation from follicular lymphoma to aggressive lymphoma historically had a poor prognosis. Routine use of anti-CD20 antibody rituximab has changed the landscape of follicular lymphoma (FL) such that outcomes are improved in select patients, similar to de-novo diffuse large B-cell lymphoma. Several biological and clinical biomarkers can predict risk of transformation, and ongoing research is improving understanding of the biology surrounding the transformation process. This review provides an overview of risk factors, prognosis, and treatment of histologic transformation of FL.
引用
收藏
页码:785 / 794
页数:10
相关论文
共 43 条
[1]   Stage I and II follicular non-Hodgkin's lymphoma: Long-term follow-up of no initial therapy [J].
Advani, R ;
Rosenberg, SA ;
Horning, SJ .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (08) :1454-1459
[2]   Population-Based Analysis of Incidence and Outcome of Transformed Non-Hodgkin's Lymphoma [J].
Al-Tourah, Abdulwahab J. ;
Gill, Karamjit K. ;
Chhanabhai, Mukesh ;
Hoskins, Paul J. ;
Klasa, Richard J. ;
Savage, Kerry J. ;
Sehn, Laurie H. ;
Shenkier, Tamara N. ;
Gascoyne, Randy D. ;
Connors, Joseph M. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (32) :5165-5169
[3]   Risk of, and survival following, histological transformation in follicular lymphoma in the rituximab era. A retrospective multicentre study by the Spanish GELTAMO group [J].
Alonso-Alvarez, Sara ;
Magnano, Laura ;
Alco-Ceba, Miguel ;
Andrade-Campos, Marcio ;
Espinosa-Lara, Natalia ;
Rodriguez, Guillermo ;
Mercadal, Santiago ;
Carro, Itziar ;
Sancho, Juan M. ;
Moreno, Miriam ;
Salar, Antonio ;
Garcia-Pallarols, Francesc ;
Arranz, Reyes ;
Cannata, Jimena ;
Terol, Maria Jose ;
Teruel, Ana I. ;
Rodriguez, Antonia ;
Jimenez-Ubieto, Ana ;
Gonzalez de Villambrosia, Sonia ;
Bello, Jose L. ;
Lopez, Lourdes ;
Monsalvo, Silvia ;
Novelli, Silvana ;
de Cabo, Erik ;
Infante, Maria S. ;
Pardal, Emilia ;
Garcia-Alvarez, Maria ;
Delgado, Julio ;
Gonzalez, Marcos ;
Martin, Alejandro ;
Lopez-Guillermo, Armando ;
Caballero, Maria D. .
BRITISH JOURNAL OF HAEMATOLOGY, 2017, 178 (05) :699-708
[4]   Sustained Progression-Free Survival Benefit of Rituximab Maintenance in Patients With Follicular Lymphoma: Long-Term Results of the PRIMA Study [J].
Bachy, Emmanuel ;
Seymour, John F. ;
Feugier, Pierre ;
Offner, Fritz ;
Lopez-Guillermo, Armando ;
Belada, David ;
Xerri, Luc ;
Catalano, John V. ;
Brice, Pauline ;
Lemonnier, Francois ;
Martin, Alejandro ;
Casasnovas, Olivier ;
Pedersen, Lars M. ;
Dorvaux, Veronique ;
Simpson, David ;
Leppa, Sirpa ;
Gabarre, Jean ;
da Silva, Maria G. ;
Glaisner, Sylvie ;
Ysebaert, Loic ;
Vekhoff, Anne ;
Intragumtornchai, Tanin ;
Le Gouill, Steven ;
Lister, Andrew ;
Estell, Jane A. ;
Milone, Gustavo ;
Sonet, Anne ;
Farhi, Jonathan ;
Zeuner, Harald ;
Tilly, Herve ;
Salles, Gilles .
JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (31) :2815-+
[5]   Incidence of transformation to aggressive lymphoma in limited-stage follicular lymphoma treated with radiotherapy [J].
Bains, P. ;
Al Tourah, A. ;
Campbell, B. A. ;
Pickles, T. ;
Gascoyne, R. D. ;
Connors, J. M. ;
Savage, K. J. .
ANNALS OF ONCOLOGY, 2013, 24 (02) :428-441
[6]   Transformed non-Hodgkin lymphoma in the rituximab era: analysis of the NCCN outcomes database [J].
Ban-Hoefen, Makiko ;
Vanderplas, Ann ;
Crosby-Thompson, Allison L. ;
Abel, Gregory A. ;
Czuczman, Myron S. ;
Gordon, Leo I. ;
Kaminski, Mark S. ;
Kelly, Jennifer ;
Millenson, Michael ;
Nademanee, Auayporn P. ;
Rodriguez, Maria A. ;
Zelenetz, Andrew D. ;
Niland, Joyce ;
LaCasce, Ann S. ;
Friedberg, Jonathan W. .
BRITISH JOURNAL OF HAEMATOLOGY, 2013, 163 (04) :487-495
[7]   Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients [J].
Bastion, Y ;
Sebban, C ;
Berger, F ;
Felman, P ;
Salles, G ;
Dumontet, C ;
Bryon, PA ;
Coiffier, B .
JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (04) :1587-1594
[8]   Transformed follicular non-Hodgkin lymphoma [J].
Casulo, Carla ;
Burack, W. Richard ;
Friedberg, Jonathan W. .
BLOOD, 2015, 125 (01) :40-47
[9]   Histologic transformation in marginal zone lymphomas [J].
Conconi, A. ;
Franceschetti, S. ;
von Hohenstaufen, K. Aprile ;
Margiotta-Casaluci, G. ;
Stathis, A. ;
Moccia, A. A. ;
Bertoni, F. ;
Ramponi, A. ;
Mazzucchelli, L. ;
Cavalli, F. ;
Gaidano, G. ;
Zucca, E. .
ANNALS OF ONCOLOGY, 2015, 26 (11) :2329-2335
[10]   Incidence, risk factors and outcome of histological transformation in follicular lymphoma [J].
Conconi, Annarita ;
Ponzio, Carlotta ;
Lobetti-Bodoni, Chiara ;
Motta, Maddalena ;
Rancoita, Paola M. V. ;
Stathis, Anastasios ;
Moccia, Alden A. ;
Mazzucchelli, Luca ;
Bertoni, Francesco ;
Ghielmini, Michele ;
Cavalli, Franco ;
Zucca, Emanuele .
BRITISH JOURNAL OF HAEMATOLOGY, 2012, 157 (02) :188-196