First total synthesis of quiquesetinerviusin A

被引：3

作者：

Xia, Yamu ^{[1
]}

Mo, Zhen ^{[1
]}

Sun, Lin ^{[1
]}

Zou, Lijia ^{[1
]}

Zhang, Wen ^{[1
]}

Zhang, Jiahong ^{[1
]}

Wang, Lihong ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Coll Chem Engn, Qingdao 266042, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2017年 / 05期

基金：

中国国家自然科学基金;

关键词：

quiquesetinerviusin A; dihydrobenzofuran neolignans; DIHYDROBENZOFURAN NEOLIGNANS; BIOACTIVE COMPOUNDS; ANTIOXIDANT; SEEDS; DERIVATIVES; LIGNANS;

D O I：

10.3184/174751917X14931195075599

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first total synthesis of the dihydrobenzofuran neolignan quiquesetinerviusin A and its related structure have been described. Phenolic coupling is the key step to constructing the dihydrobenzofuran skeleton with vanillin as the raw material. The hydroxyl group was protected with dihydropyran (DHP) and the ester group was reduced with diisobutylaluminium hydride (DIBAL-H) in order to obtain the crucial intermediate diol, which was then condensed with an acid ligand to give the desired compounds following removal of the protecting groups.

引用

页码：296 / 300

页数：5

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